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Objetivo. Determinar el comportamiento de la incidencia de brucelosis humana en México durante el periodo 2000-2011 y su relación con la brucelosis en rumiantes domésticos. Material y métodos. En estudio ecológico de series de tiempo se analizaron, mediante regresión Poisson multinivel múltiple, la incidencia de brucelosis humanas durante 2000- 2011 y la incidencia en rumiantes, y su relación con índice de desarrollo humano. Resultados. La alta incidencia de brucelosis bovina aumenta 15% la incidencia de brucelosis humana. La alta incidencia en caprinos aumenta 33% la incidencia de brucelosis humana. La presencia de casos nuevos de brucelosis ovina aumenta 13% la incidencia de brucelosis humana. Conclusiones. La brucelosis es un problema de salud pública; la presencia de la brucelosis en los rumiantes domésticos y el nivel de control de la enfermedad en ellos afecta la presencia de la enfermedad en humanos.

Objective. To identify the risk of brucellosis in the state of Tlaxcala, Mexico. Materials and methods. A diagnosis of social type was conducted in the municipalities of Huamantla, Ixtenco and Teacalco, located in the eastern region of the state. The seroprevalence of brucellosis in goats and humans was determined. Results. 46.9% of producers know the programs of vaccination against brucellosis; 19.7% apply the vaccine and 80.3% do not apply the vaccine. Huamantla had the highest seroprevalence of animal brucellosis in 66.8%; San Jose Teacalco distributes unpasteurized cheeses to a distance of 270 km, increasing the risk of infection with brucellosis. Ixtenco recorded the highest prevalence of brucellosis in humans, with 1.51%. Conclusion. The municipalities studied present risks of infection and spread of brucellosis.

Objective. To describe the seroprevalence and associated factors for brucellosis among dairy farm workers. Materials and methods. We performed a secondary analysis of a data set and sera from a previous cross-sectional study in a dairy farm. Sera were tested for Brucella spp. antibodies by the slide agglutination test. Seropositivity was defined as a titer =1:40; recent infection was titers =1:160. Results. We tested 331 human sera. Seroprevalence of brucellosis was 18.1% (60/331; 95% CI 14.1-22.7); 13.3% of them (8/60; 95% CI 5.9 - 24.5) corresponded to recent infection. Highexposure occupation (calf caretaker; OR 3.3; 95%CI 1.1 - 9.7), daily hours in contact with cows (OR 1.1; 95%CI 1.03 - 1.2), and living on-site (OR 2.2; 95% CI 1.1 - 4.4) remained independently associated with seropositivity. Conclusions. We found a high seroprevalence of brucellosis among dairy farm workers, as well as a significant association among those with prolonged and close contact with cattle. [ABSTRACT FROM AUTHOR]

Objective. To determinate the relationship of human brucellosis incidence in Mexico during 2000-2011 in relation with domestic ruminant brucellosis. Materials and methods. An ecological time series study was analyzed using multilevel poisson multiple regression, the incidence of human brucellosis during 2000-2011 and incidence in ruminants and human development index. Results. The high incidence of bovine brucellosis increased 19% the incidence of human brucellosis. The high incidence of caprine brucellosis increase 17% the incidence of human brucellosis. The presence of new cases of ovine brucellosis increased 13% the incidence rates of human brucellosis. Conclusions. Brucellosis is a public health problem in Mexico, the presence of brucellosis in domestic ruminants and the level of disease control in them affects the presence of the disease in humans. [ABSTRACT FROM AUTHOR]

Objective. To identify the risk of brucellosis in the state of Tlaxcala, Mexico. Materials and methods. A diagnosis of social type was conducted in the municipalities of Huamantla, Ixtenco and Teacalco, located in the eastern region of the state. The seroprevalence of brucellosis in goats and humans was determined. Results. 46.9% of producers know the programs of vaccination against brucellosis; 19.7% apply the vaccine and 80.3% do not apply the vaccine. Huamantla had the highest seroprevalence of animal brucellosis in 66.8%; San Jose Teacalco distributes unpasteurized cheeses to a distance of 270 km, increasing the risk of infection with brucellosis. Ixtenco recorded the highest prevalence of brucellosis in humans, with 1.51%. Conclusion. The municipalities studied present risks of infection and spread of brucellosis. [ABSTRACT FROM AUTHOR]

Objetivo. Determinar la seroprevalencia de brucelosis en trabajadores agrícolas. Material y métodos. Estudio transversal efectuado durante 1996 y 1997 en la Unidad de Salud Laboral del Centro de Salud Pública (CSP) de Castellón, España, con 482 aspirantes a su acreditación como manipulador de plaguicidas para aplicación agrícola y a quienes se les hicieron las pruebas serológicas de rosa de Bengala, seroaglutinación de Wright y Coombs antibrucela. En el análisis estadístico se estimó la prevalencia y se usó regresión logística. Resultados. 15 personas (3.1%, IC 95% 1.8%-5.1%) presentaron títulos de 1/40 o mayores a las pruebas de Wright o Coombs, y todas negativas al rosa de Bengala. No se apreció riesgo profesional elevado. Conclusiones. La prevalencia estimada fue baja.Objective. To estimate the seroprevalence of brucellosis in agricultural workers. Material and Methods. This cross-sectional study was conducted between 1996 and 1997 at Unidad de Salud Laboral del Centro de Salud Pública (CSP) in Castellon, España (Public Health Center Occupational Health Unit), among 482 subjects applying for certification to handle pesticides for agricultural use. Serologic testing consisted of rose Bengal staining, Wright's agglutination, and antibrucella Coombs tests. Statistical analysis consisted in estimation of prevalence figures and logistic regression modelling. Results. Fifteen subjects (3.1%, 95% CI 1.8%-5.1%) had titers of 1/40 or higher to Wright and/or Coombs tests; all were negative to rose Bengal staining. No high occupational risk was observed. Conclusions. A low prevalence of brucellosis was found.

Objetivo. Determinar la seroprevalencia de brucelosis en trabajadores agrícolas. Material y métodos. Estudio transversal efectuado durante 1996 y 1997 en la Unidad de Salud Laboral del Centro de Salud Pública (CSP) de Castellón, España, con 482 aspirantes a su acreditación como manipulador de plaguicidas para aplicación agrícola y a quienes se les hicieron las pruebas serológicas de rosa de Bengala, seroaglutinación de Wright y Coombs antibrucela. En el análisis estadístico se estimó la prevalencia y se usó regresión logística. Resultados. 15 personas (3.1%, IC 95% 1.8%-5.1%) presentaron títulos de 1/40 o mayores a las pruebas de Wright o Coombs, y todas negativas al rosa de Bengala. No se apreció riesgo profesional elevado. Conclusiones. La prevalencia estimada fue baja.