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Your search keyword '"I. Ansell"' showing total 2 results
Start Over Author "I. Ansell" Journal scandinavian journal of gastroenterology
2 results on '"I. Ansell"'

1. Effect of the Histamine H2-receptor Antagonist, Cimetidine, on Gastric Secretion and Serum Gastrin during Insulin Infusion in Man

Author

D. J. C. Shearman, R. C. Heading, G. Lidgard, D. C. Carter, R.F.A. Logan, J. A. H. Forrest, and I. Ansell

Subjects
medicine.medical_specialty, business.industry, Insulin, medicine.medical_treatment, Gastroenterology, Antagonist, Histamine h2 receptor antagonist, Gastric secretion, Serum gastrin, chemistry.chemical_compound, Insulin infusion, Endocrinology, chemistry, Internal medicine, medicine, Cimetidine, business, Histamine, medicine.drug
Abstract

Carter, D. C., Forrest, J. A. H., Logan, R. A., Ansell, I., Lidgard, G., Heading, R. C. & Shearman, D. J. C. Effect of the histamine H2-receptor antagonist, cimetidine, on gastric secretion and ser...

Published
1976

2. Effect of the histamine H2-receptor antagonist, cimetidine, on gastric secretion and serum gastrin during insulin infusion in Man.

Author

Carter DC, Forrest JA, Logan RA, Ansell I, Lidgard G, Heading RC, and Shearman DJ

Subjects
Adult, Depression, Chemical, Humans, Male, Pepsin A metabolism, Secretory Rate drug effects, Gastric Juice metabolism, Gastric Mucosa metabolism, Gastrins blood, Guanidines pharmacology, Histamine H2 Antagonists pharmacology, Imidazoles pharmacology, Insulin
Abstract

Cimetidine infusion (100 mg h-1) reduced the acid secretory response to insulin infusion (0.03 units Kg-1h-1) when compared to paired control tests in 6 healthy volunteers. There was no significant difference between cimetidine and control tests in terms of pepsin output or serum gastrin concentrations. Cimetidine also reduced the acid secretory response when administered after 90 minutes of insulin had established a secretory response in extended tests in 3 additional volunteers. Cimetidine may have therapeutic potential in the peptic ulcer diathesis.

Published
1976

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