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1. Broad and diverse mechanisms used by deubiquitinase family members in regulating the type I interferon signaling pathway during antiviral responses.

Author

Qingxiang Liu, Yaoxing Wu, Yunfei Qin, Jiajia Hu, Weihong Xie, Xiao-Feng Qin, F., and Jun Cui

Subjects
*TYPE I interferons, *EFFERENT pathways, *ENZYMES, *ANTIVIRAL agents, *IMMUNOPATHOLOGY
Abstract

The article cites a research study that examines the regulation of type I interferon signaling pathway by deubiquitinase enzyme (DUB) family during antiviral responses. It is said that the innate immune response conferred by type I interferons needs to be controlled to avoid immunopathology. The study found that the expression of a large fraction of DUBs underwent complex temporal alteration.

Published
2018
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