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Increasing water scarcity is of growing concern in Europe, especially in Mediterranean countries along coastlines. Wastewater reuse reduces water stress, but often requires the absence of pathogen indicators and the application of chlorine to assure residual disinfection. However, the effluent qualities of typical Wastewater Treatment Plants (WWTP) show immense chlorine demands. This makes the supply, handling and dosing of typical WWTP effluent challenging, especially in rural regions. In the work presented here, a vertical flow constructed wetland (VFCW) was combined with a small-scale solar-driven Onsite Chlorine Generation system (OCG) to further improve effluent qualities for different WWTPs and to produce chlorine stock solution directly at the site. To test different operational conditions the VFCW received WWTP effluent from a) an Activated Sludge and b) a High-Rate Algae Pond system. The VFCW reduced TSS by 92%, COD by 80%, and NH 4 by over 99% and the chlorine demand by 85%. The log-unit reduction of the VFCW/OCG system reached ≥5.1 for total coliforms and ≥4.6 for E. Coli. During VFCW passage the already high electrical conductivity further increased to beyond permissible reuse limits due to high evapotranspiration (ET) rates of the planted vegetation Arundo donax. Unique aspects of this setup were that neither chemicals nor external electricity were required to run the system. The elevated chloride concentration of the treated WW (819 ± 132 mg/L) proved sufficient for the production of chlorine stock solution. However, the solar-driven OCG system tested here consumed considerably more electricity compared to other OCGs available on the market. Nevertheless, the system presented here may be considered an efficient disinfection alternative for decentralized WW reuse applications at remote sites with both limited access to grid electricity and strict requirements for pathogen indicators. Unlabelled Image • VFCW treatment substantially reduces chlorine demand of treated wastewater. • VFCW + Onsite Chlorine Generation (OCG) provides water free of pathogen indicators. • OCG can be operated without external input of NaCl. • Polished wastewater can be reused in many applications that go beyond irrigation. • Polishing and disinfection was completely powered with a small solar PV battery system. [ABSTRACT FROM AUTHOR]