Understanding the trends in vegetation evolution and their driving factors is critical to revealing changes in ecosystem's structure and function. However, less is known about the nonlinear relationship between greening trends and greening to browning shifts in vegetation and its driving factors. Based on ensemble empirical mode decomposition (EEMD) and Boosted Regression Tree (BRT) methods, we investigated the nonlinear relationships of the greening trends and greening to browning shifts in vegetation to climate change, elevation, and human activities along the Silk Road Economic Belt (SREB). Results indicated that: (1) For vegetation with greening trends, although the total importance of climate-related variables was greater than human activities (59.57% and 35.33%, respectively), Land use changes (14.91%) and CO 2 (9.41%) were more important than the other nature-related variables. In addition, volumetric soil moisture (8.72%), precipitation of warmest quarter (6.50%), and daily snow water equivalent (5.75%) were also very important. For vegetation with greening to browning shifts, the total contributions of climate-related variables were also larger than human activities (69.10% and 19.36%, respectively). Moreover, elevation (11.54%), vapor pressure deficit (9.85%), annual mean temperature (6.84%), min temperature of the coldest month (5.98%), soil moisture (5.16%), and annual precipitation (5.11%) might be the main reasons. (2) Increased cropland and grassland, along with the land conversions from shrub land/sparse vegetated to forest could promote vegetation greening. Increased rates of CO 2 , volumetric soil moisture, warmest quarter precipitation, and daily snow water equivalent could also promote it. For vegetation with greening to browning shifts, low-altitude areas, increased vapor pressure deficit, decreased cold temperature, and drought could promote vegetation shift greening to browning. The nonlinear analysis can correctly reveal the actual trends in vegetation and its responses to driving factors, which will further provide adaptation strategies to protect ecology. Unlabelled Image • Total importance of climate-related variables was greater than human activities. • Land use changes and CO 2 were the most important for vegetation greening. • Increased cropland could promote vegetation greening. • Drought was the main reason for greening to browning. [ABSTRACT FROM AUTHOR]