1. Advancing cancer immunotherapy: from innovative preclinical models to clinical insights.
- Author
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Craig, Andrew W., Frieboes, Hermann B., and Videira, Paula A.
- Subjects
IMMUNE checkpoint inhibitors ,ANIMAL models in research ,CHIMERIC antigen receptors ,IMMUNOTHERAPY ,SCIENTIFIC knowledge ,T cell receptors ,T cells ,PROGRAMMED cell death 1 receptors - Abstract
The rapid expansion of cancer immunology and immunotherapy builds upon the success of early immune checkpoint inhibitors (ICI) and chimeric antigen receptor T cells for some cancer types. Many gaps still exist, however, in the scientific knowledge of immune dysfunction in the tumour microenvironment and predicting clinical immunotherapy response to allow more cancer patients to benefit from immunotherapy. The Cancer Immunotherapy Collection within Scientific Reports describes pioneering preclinical and clinical studies addressing these concepts, representing significant insights and breakthroughs in the field. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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