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247 results on '"Li-An Feng"'

14. Precise diagnosis of three top cancers using dbGaP data

Author

Liu, Xu-Qing, Liu, Xin-Sheng, Rong, Jian-Ying, Gao, Feng, Wu, Yan-Dong, Deng, Chun-Hua, Jiang, Hong-Yan, Li, Xiao-Feng, Chen, Ye-Qin, Zhao, Zhi-Guo, Liu, Yu-Ting, Chen, Hai-Wen, Li, Jun-Liang, Huang, Yu, Ji, Cheng-Yao, Liu, Wen-Wen, Luo, Xiao-Hu, and Xiao, Li-Li

Published
2021
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39. Crack mechanism and experimental verification on straightening of AZ31B magnesium alloy plate.

Author

Wang, Rong-Jun, Zhou, Qi, Du, Xiao-Zhong, Li, Yu-Shan, Zhang, Peng-Chong, Li, Guang-Feng, Huang, Zhi-Quan, Ma, Li-Dong, and Jiang, Lian-Yun

Subjects
ALLOY plating, STRAINS & stresses (Mechanics), MAGNESIUM alloys, POROSITY, FRACTURE mechanics, STRESS concentration
Abstract

When plates with edge cracks in the rolling process is straightened by cyclic tensile and compressive stress, the tip of edge crack always accompanied by stress concentration, which leads to crack propagation. In this paper, damage parameters are imported into the plate straightening model based on determining the GTN damage parameters of magnesium alloy materials by inverse finite element calibration method, the influence of different straightening process schemes and prefabricated V-shaped crack geometry on crack growth is analyzed through the way of the combination of simulation and straightening experiment. The results show that the peak values of equivalent stress and equivalent strain under each straightening roll appear at the crack tip. The value of longitudinal stress and equivalent stain decrease with the distance to crack tip becomes larger. The peak value of longitudinal stress appears when the crack circumferential angle is about 100°, and the crack tip is easy to form crack propagation; when the plate passes roll 2 and roll 4, the equivalent stress and strain concentration at the crack tip are most obvious; when the reduction reaches a certain degree, the void volume fraction (VVF) reaches the VVF of the material breaking; with the increase of the entrance reduction, the number of VVF at the crack tip which reaches the material fracture increases, and the length of crack propagation increases; the stress concentration at the tip of V-shaped crack with large length–width ratio is obvious, and the VVF is more likely to reach the VVF at the time of material fracture, crack initiates and propagates easily. [ABSTRACT FROM AUTHOR]

Published
2023
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43. Novel risk models to predict acute kidney disease and its outcomes in a Chinese hospitalized population with acute kidney injury

Author

Ye-Qing Xiao, Shi-Kun Yang, Ying-Hao Deng, Wei Cheng, Shao-Bin Duan, Li-Xin Feng, Jin-Cheng Peng, Xi Wu, Hong-Shen Wang, Xiang-Jie Duan, Ning-Ya Zhang, Song Feng, Fei Zhao, Qian Liu, Xu-Wei Li, and Ping Yan

Subjects
Male, medicine.medical_specialty, China, Population, 030232 urology & nephrology, lcsh:Medicine, 030204 cardiovascular system & hematology, urologic and male genital diseases, Risk Assessment, Article, End stage renal disease, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, Oliguria, Internal medicine, medicine, Humans, lcsh:Science, education, Aged, education.field_of_study, Multidisciplinary, Kidney diseases, business.industry, Mortality rate, lcsh:R, Hazard ratio, Acute kidney injury, Acute Kidney Injury, medicine.disease, Prognosis, Survival Analysis, Hospitalization, Risk factors, Outcomes research, lcsh:Q, Anuria, Female, medicine.symptom, business, Kidney disease
Abstract

Acute kidney disease (AKD) is a state between acute kidney injury (AKI) and chronic kidney disease (CKD), but the prognosis of AKD is unclear and there are no risk-prediction tools to identify high-risk patients. 2,556 AKI patients were selected from 277,898 inpatients of three affiliated hospitals of Central South University from January 2015 to December 2015. The primary point was whether AKI patients developed AKD. The endpoint was death or end stage renal disease (ESRD) 90 days after AKI diagnosis. Multivariable Cox regression was used for 90-day mortality and two prediction models were established by using multivariable logistic regression. Our study found that the incidence of AKD was 53.17% (1,359/2,556), while the mortality rate and incidence of ESRD in AKD cohort was 19.13% (260/1,359) and 3.02% (41/1,359), respectively. Furthermore, adjusted hazard ratio of mortality for AKD versus no AKD was 1.980 (95% CI 1.427–2.747). In scoring model 1, age, gender, hepatorenal syndromes, organic kidney diseases, oliguria or anuria, respiratory failure, blood urea nitrogen (BUN) and acute kidney injury stage were independently associated with AKI progression into AKD. In addition, oliguria or anuria, respiratory failure, shock, central nervous system failure, malignancy, RDW-CV ≥ 13.7% were independent risk factors for death or ESRD in AKD patients in scoring model 2 (goodness-of fit, P1 = 0.930, P2 = 0.105; AUROC1 = 0.879 (95% CI 0.862–0.896), AUROC2 = 0.845 (95% CI 0.813–0.877), respectively). Thus, our study demonstrated AKD was independently associated with increased 90-day mortality in hospitalized AKI patients. A new prediction model system was able to predict AKD following AKI and 90-day prognosis of AKD patients to identify high-risk patients.

Published
2020

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