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4 results on '"Maria Pokorska-Śpiewak"'

1. COVID-19 infections in infants

Author

Małgorzata Sobolewska-Pilarczyk, Maria Pokorska-Śpiewak, Anna Stachowiak, Magdalena Marczyńska, Ewa Talarek, Agnieszka Ołdakowska, Izabela Kucharek, Adam Sybilski, Anna Mania, Magdalena Figlerowicz, Katarzyna Mazur-Melewska, Paulina Potocka, Artur Sulik, Barbara Hasiec, Martyna Stani, Paulina Frańczak-Chmura, Barbara Szczepańska, Ilona Pałyga-Bysiecka, Przemysław Ciechanowski, Joanna Łasecka-Zadrożna, Izabela Zaleska, Leszek Szenborn, Urszula Dryja, Ernest Kuchar, Sławomira Niedźwiecka, Bolesław Kalicki, Robert Flisiak, and Małgorzata Pawłowska

Subjects
Medicine, Science
Abstract

Abstract The study aimed to analyse the clinical course of COVID-19 in 300 infants, selected from 1283 children diagnosed with COVID-19 between March and December 2020, registered in the SARSTerPED multicenter database. Most of the infants were registered in October and November 2020. 44% of the group were girls, and 56% were boys. At diagnosis, the most common symptoms were fever in 77% of the children, cough in 40%, catarrh in 37%. Pneumonia associated with COVID-19 was diagnosed in 23% of the children, and gastrointestinal symptoms in 31.3%. In 52% of the infants, elevated levels of D-dimers were observed, and in 40%, elevated levels of IL-6 serum concentration were observed. During the second wave of the pandemic, 6 times more infants were hospitalized, and the children were statistically significantly younger compared to the patients during the first wave (3 months vs 8 months, p

Published
2022
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2. Comparison of clinical severity and epidemiological spectrum between coronavirus disease 2019 and influenza in children

Author

Maria Pokorska-Śpiewak, Ewa Talarek, Jolanta Popielska, Karolina Nowicka, Agnieszka Ołdakowska, Konrad Zawadka, Barbara Kowalik-Mikołajewska, Anna Tomasik, Anna Dobrzeniecka, Marta Lipińska, Beata Krynicka-Czech, Urszula Coupland, Aleksandra Stańska-Perka, Małgorzata Ludek, and Magdalena Marczyńska

Subjects
Medicine, Science
Abstract

Abstract Data on the novel coronavirus disease 2019 (COVID-19) in children are limited, and studies from Europe are scarce. We analyzed the clinical severity and epidemiologic aspects of COVID-19 in consecutive children aged 0–18 years, referred with a suspicion of COVID-19 between February 1, and April 15, 2020. RT-PCR on a nasopharyngeal swab was used to confirm COVID-19. 319 children met the criteria of a suspected case. COVID-19 was diagnosed in 15/319 (4.7%) patients (8 male; mean age 10.5 years). All of them had household contact with an infected relative. Five (33.3%) patients were asymptomatic. In 9/15 (60.0%) children, the course of the disease was mild, and in 1/15 (6.7%), it was moderate, with the following symptoms: fever (46.7%), cough (40%), diarrhea (20%), vomiting (13.3%), rhinitis (6.7%), and shortness of breath (6.7%). In the COVID-19-negative patients, other infections were confirmed, including influenza in 32/319 (10%). The clinical course of COVID-19 and influenza differed significantly based on the clinical presentation. In conclusion, the clinical course of COVID-19 in children is usually mild or asymptomatic. In children suspected of having COVID-19, other infections should not be overlooked. The main risk factor for COVID-19 in children is household contact with an infected relative.

Published
2021
Full Text
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3. COVID-19 infections in infants

Author

Małgorzata Sobolewska-Pilarczyk, Maria Pokorska-Śpiewak, Anna Stachowiak, Magdalena Marczyńska, Ewa Talarek, Agnieszka Ołdakowska, Izabela Kucharek, Adam Sybilski, Anna Mania, Magdalena Figlerowicz, Katarzyna Mazur-Melewska, Paulina Potocka, Artur Sulik, Barbara Hasiec, Martyna Stani, Paulina Frańczak-Chmura, Barbara Szczepańska, Ilona Pałyga-Bysiecka, Przemysław Ciechanowski, Joanna Łasecka-Zadrożna, Izabela Zaleska, Leszek Szenborn, Urszula Dryja, Ernest Kuchar, Sławomira Niedźwiecka, Bolesław Kalicki, Robert Flisiak, and Małgorzata Pawłowska

Subjects
Male, Multidisciplinary, COVID-19 Testing, SARS-CoV-2, COVID-19, Humans, Infant, Female, Pneumonia, Child, Pandemics
Abstract

The study aimed to analyse the clinical course of COVID-19 in 300 infants, selected from 1283 children diagnosed with COVID-19 between March and December 2020, registered in the SARSTerPED multicenter database. Most of the infants were registered in October and November 2020. 44% of the group were girls, and 56% were boys. At diagnosis, the most common symptoms were fever in 77% of the children, cough in 40%, catarrh in 37%. Pneumonia associated with COVID-19 was diagnosed in 23% of the children, and gastrointestinal symptoms in 31.3%. In 52% of the infants, elevated levels of D-dimers were observed, and in 40%, elevated levels of IL-6 serum concentration were observed. During the second wave of the pandemic, 6 times more infants were hospitalized, and the children were statistically significantly younger compared to the patients during the first wave (3 months vs 8 months, p

Published
2021

4. Comparison of clinical severity and epidemiological spectrum between coronavirus disease 2019 and influenza in children

Author

Agnieszka Ołdakowska, Anna Dobrzeniecka, Aleksandra Stańska-Perka, Jolanta Popielska, Urszula Coupland, Beata Krynicka-Czech, Małgorzata Ludek, Anna Tomasik, Konrad Zawadka, Maria Pokorska-Śpiewak, Marta Lipińska, Barbara Kowalik-Mikołajewska, Karolina Nowicka, Ewa Talarek, and Magdalena Marczyńska

Subjects
Male, Pediatrics, medicine.medical_specialty, Coronavirus disease 2019 (COVID-19), Adolescent, Science, Disease, Asymptomatic, Article, 03 medical and health sciences, 0302 clinical medicine, Medical research, 030225 pediatrics, Epidemiology, Influenza, Human, medicine, Humans, 030212 general & internal medicine, Prospective Studies, Risk factor, Prospective cohort study, Child, Multidisciplinary, business.industry, Infant, Newborn, Health care, COVID-19, Infant, Diarrhea, Child, Preschool, Vomiting, Medicine, Female, Poland, medicine.symptom, business
Abstract

Data on the novel coronavirus disease 2019 (COVID-19) in children are limited, and studies from Europe are scarce. We analyzed the clinical severity and epidemiologic aspects of COVID-19 in consecutive children aged 0–18 years, referred with a suspicion of COVID-19 between February 1, and April 15, 2020. RT-PCR on a nasopharyngeal swab was used to confirm COVID-19. 319 children met the criteria of a suspected case. COVID-19 was diagnosed in 15/319 (4.7%) patients (8 male; mean age 10.5 years). All of them had household contact with an infected relative. Five (33.3%) patients were asymptomatic. In 9/15 (60.0%) children, the course of the disease was mild, and in 1/15 (6.7%), it was moderate, with the following symptoms: fever (46.7%), cough (40%), diarrhea (20%), vomiting (13.3%), rhinitis (6.7%), and shortness of breath (6.7%). In the COVID-19-negative patients, other infections were confirmed, including influenza in 32/319 (10%). The clinical course of COVID-19 and influenza differed significantly based on the clinical presentation. In conclusion, the clinical course of COVID-19 in children is usually mild or asymptomatic. In children suspected of having COVID-19, other infections should not be overlooked. The main risk factor for COVID-19 in children is household contact with an infected relative.

Published
2020

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