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66 results on '"Single-domain antibodies"'

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1. TEMPRO: nanobody melting temperature estimation model using protein embeddings

2. TEMPRO: nanobody melting temperature estimation model using protein embeddings.

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3. A camelid single-domain antibody neutralizes botulinum neurotoxin A by blocking host receptor binding.

4. Fully automated

5. Anti-CfaE nanobodies provide broad cross-protection against major pathogenic enterotoxigenic Escherichia coli strains, with implications for vaccine design

6. A multispecies competitive nanobody-based ELISA for the detection of antibodies against hepatitis E virus.

7. Co-administration of an effector antibody enhances the half-life and therapeutic potential of RNA-encoded nanobodies.

8. Discovery and multimerization of cross-reactive single-domain antibodies against SARS-like viruses to enhance potency and address emerging SARS-CoV-2 variants.

9. Intramuscular delivery of formulated RNA encoding six linked nanobodies is highly protective for exposures to three Botulinum neurotoxin serotypes

10. Antibody-nanobody combination increases their neutralizing activity against SARS-CoV-2 and nanobody H11-H4 is effective against Alpha, Kappa and Delta variants

11. Construction of a T7 phage display nanobody library for bio-panning and identification of chicken dendritic cell-specific binding nanobodies

12. Development and characterization of a camelid derived antibody targeting a linear epitope in the hinge domain of human PCSK9 protein

13. First-in-class trispecific VHH-Fc based antibody with potent prophylactic and therapeutic efficacy against SARS-CoV-2 and variants

14. Enzymatic ligation of an antibody and arginine 9 peptide for efficient and cell-specific siRNA delivery

15. Gold conjugated nanobodies in a signal-enhanced lateral flow test strip for rapid detection of SARS-CoV-2 S1 antigen in saliva samples.

16. Nanobody-based CTLA4 inhibitors for immune checkpoint blockade therapy of canine cancer patients

17. Delicate balance among thermal stability, binding affinity, and conformational space explored by single-domain VHH antibodies

18. Bivalent single domain antibody constructs for effective neutralization of Venezuelan equine encephalitis

19. Peptide barcoding for one-pot evaluation of sequence-function relationships of nanobodies

20. The VH framework region 1 as a target of efficient mutagenesis for generating a variety of affinity-matured scFv mutants

21. Defining the epitope of a blood–brain barrier crossing single domain antibody specific for the type 1 insulin-like growth factor receptor

22. Structure-based engineering of anti-GFP nanobody tandems as ultra-high-affinity reagents for purification

23. Nanobodies targeting ABCC3 for immunotargeted applications in glioblastoma.

24. Fully automated 18 F-fluorination of N-succinimidyl-4-[ 18 F]fluorobenzoate ([ 18 F]SFB) for indirect labelling of nanobodies.

25. Development of a Nanobody-based lateral flow assay to detect active Trypanosoma congolense infections

26. Anticancer activity and antibody-dependent cell-mediated cytotoxicity of novel anti-nucleolin antibodies

27. Evaluation and selection of potent fluorescent immunosensors by combining fluorescent peptide and nanobodies displayed on yeast surface

28. The activity of myeloid cell-specific VHH immunotoxins is target-, epitope-, subset- and organ dependent

29. Nanobody-based sandwich reporter system for living cell sensing influenza A virus infection

30. Structural and thermodynamic basis for the recognition of the substrate-binding cleft on hen egg lysozyme by a single-domain antibody

31. Nb-induced stabilisation of p53 in HPV-infected cells

32. Development and characterization of a camelid derived antibody targeting a linear epitope in the hinge domain of human PCSK9 protein.

33. Construction of a T7 phage display nanobody library for bio-panning and identification of chicken dendritic cell-specific binding nanobodies.

34. Antibody-nanobody combination increases their neutralizing activity against SARS-CoV-2 and nanobody H11-H4 is effective against Alpha, Kappa and Delta variants.

35. Author Correction: Development of humanized tri-specific nanobodies with potent neutralization for SARS-CoV-2

36. An improved yeast surface display platform for the screening of nanobody immune libraries

37. Selection and Characterization of Anti-Dengue NS1 Single Domain Antibodies

38. Computational design and characterization of nanobody-derived peptides that stabilize the active conformation of the β

39. Neutralization of Junín virus by single domain antibodies targeted against the nucleoprotein

40. Nanobody-Displaying Flagellar Nanotubes

41. Intracellular immunization against HIV infection with an intracellular antibody that mimics HIV integrase binding to the cellular LEDGF protein

42. Yeast display biopanning identifies human antibodies targeting glioblastoma stem-like cells

43. TNFR1 inhibition with a Nanobody protects against EAE development in mice

44. Selection of nanobodies with broad neutralizing potential against primary HIV-1 strains using soluble subtype C gp140 envelope trimers

45. Efficient generation of single domain antibodies with high affinities and enhanced thermal stabilities

46. Determination of Aspergillus pathogens in agricultural products by a specific nanobody-polyclonal antibody sandwich ELISA

47. Bi-specific molecule against EGFR and death receptors simultaneously targets proliferation and death pathways in tumors

48. Nanobodies effectively modulate the enzymatic activity of CD38 and allow specific imaging of CD38

49. Specificity Evaluation and Disease Monitoring in Arthritis Imaging with Complement Receptor of the Ig superfamily targeting Nanobodies

50. Identification of a nanobody specific to human pulmonary surfactant protein A