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15 results on '"Tham, Yih Chung"'

12. Lamina Cribrosa Curvature in Healthy Korean Eyes

Author

Tan, Nicholas, Tham, Yih-Chung, Thakku, Sri Gowtham, Wang, Xiaofei, Baskaran, Mani, Tan, Marcus, Mari, Jean-Martial, Strouthidis, NIcholas, Aung, Tin, Cheng, Ching-Yu, Lee, Seung Hyen, Kim, Tae-Woo, Lee, Eun Ji, Girard, Michaël, Laboratoire de Chimie des Processus Biologiques (LCPB), Collège de France (CdF (institution))-Institut de Chimie du CNRS (INC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Géopôle du Pacifique Sud (GePaSUD), Université de la Polynésie Française (UPF), and Duke-NUS Medical School [Singapore]

Subjects
Adult, Male, 0301 basic medicine, medicine.medical_specialty, Lamina, genetic structures, Optic Disk, Glaucoma, lcsh:Medicine, Curvature, Article, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Optical coherence tomography, Ophthalmology, [INFO.INFO-IM]Computer Science [cs]/Medical Imaging, Humans, Medicine, lcsh:Science, ComputingMilieux_MISCELLANEOUS, Aged, Multidisciplinary, medicine.diagnostic_test, business.industry, Healthy population, lcsh:R, Healthy subjects, Middle Aged, medicine.disease, eye diseases, 030104 developmental biology, medicine.anatomical_structure, Biological Variation, Population, Population Surveillance, Female, lcsh:Q, Enhanced depth imaging, sense organs, Factor Analysis, Statistical, business, Tomography, Optical Coherence, 030217 neurology & neurosurgery, Optic disc
Abstract

Given that posterior bowing of the lamina cribrosa (LC) is a principle event in the development of glaucomatous damage, assessment of the LC morphology may have clinical utility in diagnosing and managing glaucoma patients. LC curvature has been suggested as an index to evaluate the LC morphology. To apply LC morphology in clinical practice, it is necessary to know normal profiles of LC curvature in healthy population. This study was performed to investigate the characteristics of LC curvature in healthy eyes using enhanced depth imaging spectral-domain optical coherence tomography in a total of 250 eyes of 125 healthy Korean subjects. The lamina cribrosa curvature index (LCCI) values at seven locations spaced equidistantly across the vertical optic disc diameter were measured on serial horizontal B-scan images. The mean value of the seven measurements was defined as the average LCCI. The average LCCI was 7.46 ± 1.22 (range, 4.29–10.48) and did not differ significantly between the right and left eyes. There was a strong inter-eye correlation within subjects. LCCI was significantly larger in eyes with shorter axial length (P

Published
2019

14. Genome-wide association study identifies a missense variant at APOA5 for coronary artery disease in Multi-Ethnic Cohorts from Southeast Asia

Author

Han, Yi, primary, Dorajoo, Rajkumar, additional, Chang, Xuling, additional, Wang, Ling, additional, Khor, Chiea-Chuen, additional, Sim, Xueling, additional, Cheng, Ching-Yu, additional, Shi, Yuan, additional, Tham, Yih Chung, additional, Zhao, Wanting, additional, Chee, Miao Ling, additional, Sabanayagam, Charumathi, additional, Chee, Miao Li, additional, Tan, Nicholas, additional, Wong, Tien Yin, additional, Tai, E-Shyong, additional, Liu, Jianjun, additional, Goh, Daniel Y. T., additional, Yuan, Jian-Min, additional, Koh, Woon-Puay, additional, van Dam, Rob M., additional, Low, Adrian F., additional, Chan, Mark Yan-Yee, additional, Friedlander, Yechiel, additional, and Heng, Chew-Kiat, additional

Published
2017
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