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4 results on '"Xinru Li"'

1. Large gap Quantum Spin Hall Insulators of Hexagonal III-Bi monolayer

Author

Xinru Li, Qunqun Liu, Chengwang Niu, Tiejun Li, Ying Dai, Yandong Ma, and Baibiao Huang

Subjects
Multidisciplinary, Materials science, Condensed matter physics, Spintronics, Hexagonal crystal system, Electronic band, 02 engineering and technology, 021001 nanoscience & nanotechnology, 01 natural sciences, Electron velocity, Article, Quantum spin Hall effect, 0103 physical sciences, Monolayer, First principle, Edge states, 010306 general physics, 0210 nano-technology
Abstract

In the present work, we demonstrate that both GaBi3 and InBi3 monolayers are Quantum Spin Hall insulators. Here, the electronic band structures and edge states of the two novel monolayers are systematically investigated by first principle calculation. Our analysis of the band inversion and Z2 number demonstrate that both GaBi3 and InBi3 are promising 2D TIs with large gaps of 283meV and 247meV, respectively. Taking GaBi3 as example, it is illustrated that the edge states are impacted by SOC and finite size effect. In addition, it is found that the compression and tension totally affect differently on the edge states. Finally, the electron velocity is studied in detail, which is highly important in the manufacturing of spintronics device.

Published
2016

2. FasL gene -844T/C mutation of esophageal cancer in South China and its clinical significance

Author

Xinru Li, Hongguang Zhao, Lifang Wang, and Linfeng Zheng

Subjects
Oncology, Male, Risk, medicine.medical_specialty, China, South china, Fas Ligand Protein, Esophageal Neoplasms, Genotype, chemical and pharmacologic phenomena, Polymorphism, Single Nucleotide, Fas ligand, Article, Risk Factors, Internal medicine, medicine, Humans, Clinical significance, Genetic Predisposition to Disease, Gene, neoplasms, Alleles, Multidisciplinary, business.industry, hemic and immune systems, Esophageal cancer, Middle Aged, medicine.disease, digestive system diseases, Case-Control Studies, Mutation (genetic algorithm), Mutation, Carcinoma, Squamous Cell, Female, Esophageal Squamous Cell Carcinoma, biological phenomena, cell phenomena, and immunity, business
Abstract

In this study, we investigated the association between the FasL -844T/C polymorphism and the risk of developing esophageal squamous cell carcinoma (ESCC) in South China. For the investigation, we randomly selected 248 patients suffering from ESCC from Southern China along with 297 healthy individuals as the control group. The relationship between the FasL gene -844T/C SNP and ESCC was studied using PCR-RFLP and immunohistochemistry. The Fas -1377G/A SNP was also selected for investigation to detect whether it interferes with the functional effect of the FasL -844C/T polymorphism in ESCC development. A significant difference in the FasL -844T/C genotypes between the patients and the control group was observed (P

Published
2013

3. FasL Gene -844T/C Mutation of Esophageal Cancer in South China and Its Clinical Significance.

Author

Hongguang Zhao, Linfeng Zheng, Xinru Li, and Lifang Wang

Subjects
SQUAMOUS cell carcinoma, ESOPHAGEAL cancer, GENETIC polymorphisms, IMMUNOHISTOCHEMISTRY, ALLELES
Abstract

In this study, we investigated the association between the FasL -844T/C polymorphism and the risk of developing esophageal squamous cell carcinoma (ESCC) in South China. For the investigation, we randomly selected 248 patients suffering from ESCC from Southern China along with 297 healthy individuals as the control group. The relationship between the FasL gene -844T/C SNP and ESCC was studied using PCR-RFLP and immunohistochemistry. The Fas -1377G/A SNP was also selected for investigation to detect whether it interferes with the functional effect of the FasL -844C/T polymorphism in ESCC development. A significant difference in the FasL -844T/C genotypes between the patients and the control group was observed (P<0.05), with those expressing the C allele having a significantly reduced risk of developing ESCC, however elderly patients (>60 years) exhibited amoremalignant pathological grade if they were homozygous for the C allele. FasL -844 CC combined with the Fas -1377 G allele is a protective factor against ESCC. Having said this, even though the C allele has a protective effect prior to development of ESCC, once the host does develop the condition the tumour will develop faster and have a higher degree of malignancy than T carriers [ABSTRACT FROM AUTHOR]

Published
2014
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