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To assess the value of carbon nanoparticles which mapping sentinel lymph node (SLN) and predict the status of lymph node metastasis status in the early gastric cancer (EGC), and to explore the SLN distribution.Forty five patients with EGC, who underwent surgical treatment, were enrolled. At the completion of exploratory laparotomy, 1 mL solution of carbon nanoparticles was injected subserosally in the gastric wall 4-6 sites around the primary tumor during surgery in all patients. The first stained lymph nodes were defined as the SLN. Postoperative SLN and dissection of the lymph node was sent for histopathological examination.Carbon nanoparticles were applied in 45 EGC patients for mapping SLN and 43 cases (95.6%) were observed with positive stain. 53 pieces of SLN were detected, average (1.23 +/- 0.53) pieces for one person. 11 of the 43 patients (25.6%) developed lymph node metastasis, through the SLN histopathological examination, 3 cases (7.0%) were false negative, the accuracy and sensitivity of the prediction of regional lymph node metastasis status was 93.0% and 72.7%, respectively. The false negative and negative predictive value was 27.3% and 91.4%. There were significant differences between the mucosal cancer group and submucous cancer group in the diameter of tumor (P = 0.042) and the rate of lymph node metastasis (P = 0.001). There were no significant differences between the two groups in the accuracy and sensitivity (P0.05). In 36 cases of gastric cancer patients, 23 SLN positive cases (63.9%) were detected in third group.The dyeing rate, accuracy and sensitivity of carbon nanoparticles mapping SLN for EGC were high. Carbon nanoparticles mapping SLN can more accurately predict perigastric lymph node metastasis status in patients with EGC.

To evaluate the outcome of gastric tube anastomosis after intraperitoneal gastrectomy in the patients with types II and III adenocarcinoma of the esophagogastric junction (AEG). From October 2009 to December 2010, 74 patients with diagnosis of type II or type III AEG were divided groups. Traditional anastomosis of gastric remnant with esophagus was performed to 38 patients in group, while new anastomosis of gastric tube with esophagus was performed to 34 patients in gastric tubeThere were no statistically significant differences in baseline data, clinical and pathological characteristics between the two groups (P0.05). For the postoperative complications, 12 (31.6%) patients in traditional and 4 (11.8%) patients in gastric tube group occurred gastroesophageal reflux symptoms (P = 0.043). 9 patients in traditional group and 2 (5.9%) patients in gastric tube group were diagnosed as reflux esophagitis postoperative endoscopic examination (P = 0.036).The anastomosis of gastric tube with the after proximal gastrectomy could reduce the incidence of gastroesophageal reflux.

To investigate the clinical pathological characteristics, choice of surgical therapy and postoprative complications of patients with types II and III adenocarcinoma of esophagogastric junction (AEG).Clinical data of 112 patients with types II and III AEG who underwent intraperiteanal operations from January 2008 to July 2010 were reviewed. Amongst the patients, 77 suffered from type II AEG and 35 suffered from type III AEG; 72 underwent proximal gastrectomy and 40 underwent total gastrectomy.The patients with type II and type III AEG shared some common characteristics, such as advanced tumor TNM stage and lymphatic metastasis. There was a significant difference in choice of surgical approaches between the two groups of patients (P0.05), with 57 type II AEG patients (74.0%) and 15 type III AEG patients (42.9%) undergoing proximal gastrectomy respectively. Operational time and incidence of postoperative complications differed between proximal gastrectomy and total gastrectomy (P0.05). Total gastrectomy lasted longer [(304.12 +/- 23.12) min] than proximal gastrectomy [(275.76 +/- 27.02) min]. Proximal gastrectomy provoked 20.8% (15 patients) heartburn and/or acid regurgitation and 12.5% (9 cases) reflux esophagitis. Fifteen patients (37.5%) with total gastrectomy had more than 5 meals a day.Intraperiteanal operations are recommended for patients with types IT and Ili AEG. The choice of proximal gastrectomy or total gastrectomy depends on the location and size of the tumor, both being followed with some complications.