Search

Eccrine porocarcinoma is a rare neoplasma which differentiates toward intraepidermal eccrine sweat duct. We experienced a 73-year-old man who suffered from a tumor on the right forearm. The tumor was 95×76×60mm in size, dark red and pedunculated, and had been growing slowly in the last 40 years. Histopathological findings showed the irregularly outlined nests which were continuous to the epidermis. The tumor cells had atypical nuclei and clear cytoplasms. The clear cells were partially vacuolated. In addition to ductal and cystic structures, cuticle formation was also present.Wide local excision and lymph node dissections of antecubital and axillary areas were performed, and postoperative adjuvant radiation was added to the regional lymph node areas. However, 1.5 years later after operation, he died of lung metastasis.

A 57-year-old female case with a malignant eccrine tumor of the chest was reported. On clinical inspection she noticed the tumor 6 months before, and the tumor had gradually become bigger with some slight tenderness. First surgical excision of tumor was performed under the general anesthesia, followed to be diagnosed eccrine spirocarcinoma histologically. However, she noticed small tumor on the left axilla 11 months after the first operation and second surgical wide excision with lymphosectomy was performed to confirm metastasis. After second operation, she had radiation therapy and no recurrence has been observed for these 2 years. The classification of malignant eccrine tumor was reported by Mishima and Morioka 1968. Since this report, some cases have reported in Japan. In this report, clinical and histological findings of our case was studied and discussed.

A 50-year-old Japanese female of acral lentiginous melanoma in situ involved into deeper eccrine duct epithelium on the right middle finger was described. Histopathologically, increased number of atypical melanocytes were proliferated involving both lower epidermis and deeper portion, 643μm from epidermal basal layer, of eccrine sweat duct epithelium, which is a rare histological finding in usual ALM. It is well known and interesting that malignant melanoma in situ, especially ALM in situ often proliferate involving into superficial portion of eccrine duct epithelium, however, our case was exceptional.We supposed that ALM in situ cells could proliferate with affinity to eccrine duct epitherlium. Taken together, we need careful treatment and follow-up for ALM in situ with proliferation into the deeper portion of eccrine duct as our case.