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Cloud data sharing allows users to access data stored on the web object. Security and protecting cloud data sharing form different attacks is recently considered one of the most challenges. In this paper, we are proposing a framework for cloud data sharing protection against unauthorized access. The proposed framework is based on DNA-proxy re-encryption. Firstly, three keys are generated for the owner, proxy and the user who need to access the data. Then, the owner stores his data encrypted on the cloud using his key. If the user wants to access this data then he can access it via the proxy after re-encrypting using the second generated key for the proxy. Finally, the user can decrypt the re-encrypted data with the third generated key. The framework was implemented using various plaintext files and real DNA sequences. The experimental results show that the framework has an outstanding performance in terms of execution time. [ABSTRACT FROM AUTHOR]