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[Display omitted] • The nitrogen heterocycles improve the application value of salamo compounds. • It is rare that the probe can recognize anions stably in a solution with high water content. • The probe achieves the purpose of recognition by oxidative hydrolysis of C = N bond. A unique fluorescent probe Ni-DAS was developed by a nitrogenous heterocyclic oligo(N,O-donor) salamo-based compound DAS. DAS exhibits AIE and ESIPT effects which are extremely infrequent in salamo-based multi-oxime compounds. In addition, Ni-DAS can be used as a fluorescent probe with high selectivity and sensitivity to recognize Cr 2 O 7 2- in DMF with 80 % water content, which enhances the value of the probe for application in real environments, and outperforms most similar molecular fluorescence probes. The probe Ni-DAS can recognize Cr 2 O 7 2- by oxidative hydrolysis of C = N bonds, which promotes further research on theory of C = N bond hydrolysis, and the binding ratio and recognition mechanism were verified and supported by relevant theoretical calculations (DFT & MESP). The experiments showed that the probe Ni-DAS can be used for ion detection in real environments. It provides a new strategy for the oxidative hydrolysis of C = N bond and the structure of salamo-based compounds with AIE nature, and offers new ideas for study ion recognition and acidity detection. [ABSTRACT FROM AUTHOR]

• A lysosome-targetable two-photon excited near-infrared fluorescent probe, Lyso-TP-HClO , was developed for HClO. • Lyso-TP-HClO exhibited the advantages of small autofluorescence, excellent photostability and large imaging depth. • Lyso-TP-HClO was successfully applied for imaging the arthritis and evaluating the treatment of arthritis by drug in mice. Lysosome of phagocyte is the main site of hypochlorous acid (HClO) production, and HClO can be employed as the biomarker for the diagnosis and treatment evaluation of arthritis. In recent years, developing fluorescent probes for lysosomal HClO has attracted considerable attention, but most of them still have some defects, such as autofluorescence, phototoxicity and photobleaching because of their excitation and emission located in short-wavelength region. Due to the advantages of two-photon fluorescent probes with near-infrared emissions, a lysosome-targetable two-photon fluorescent probe (Lyso-TP-HClO) with a near-infrared emission was reported in this paper. Lyso-TP-HClO has a high selectivity and a high sensitivity to HClO in the linear range (10.0 × 10−8 to 5.0 × 10−6 M), with a detection limit of 3.0 × 10−8 M. Due to the two-photon excited near-infrared emission, Lyso-TP-HClO has excellent imaging performances, such as small autofluorescence, excellent photostability, and large imaging depth. Furthermore, Lyso-TP-HClO was successfully employed for visualizing lysosomal HClO in bacteria-infected cells. At last, we have successfully used Lyso-TP-HClO to image the arthritis and evaluate the treatment of arthritis in mice. All the results confirm that Lyso-TP-HClO is a useful chemical tool for imaging of lysosomal HClO, the diagnosis of arthritis, and treatment evaluation of arthritis. [ABSTRACT FROM AUTHOR]

A novel bis(salamo)-like probe FT was successfully determined, it prescented fluorescent decreased phenomenon for Fe3+ and Cu2+ ions and colorimetric sensing ability towards Cu2+ ions, and excellent applicability were constructed in test filter paper to highly sensitive monitoring Fe3+ and Cu2+ ions. [Display omitted] • A novel and effective bis(salamo)-like probe FT was first successfully developed. • FT uses as a fluorescent ON-OFF probe for Fe3+ and Cu2+ ions. • Theoretical calculations were further applied to explore electronic properties. • FT was employed for monitoring Fe3+ and Cu2+ via test filter paper in real time. A novel bis(salamo)-type sensor FT for fluorescence-colorimetric recognition of Fe3+/Cu2+ has been created, which revealed significant fluorescent performance and colorimetric sensing ability for Cu2+ and Fe3+ ions, superior to other related competitive metal ions. Interestingly, the binding of the FT probe with Cu2+ ions manifested an instant color change from colorless to red in sunlight, which is detectable by the naked-eye, and a fluorescence turn-off response under UV light for Fe3+ and Cu2+. The results demonstrated that the probe exhibits better sensitivity, greater affinity and lower limit of detection leading to quick response time in an aquo-organic medium. The excited state property of the FT probe and in the presence of Cu2+/Fe3+ was evaluated on the basis of DFT & TD-DFT results. Furthermore, test strips have been provided for convenient monitoring of Cu2+ and Fe3+ ions by naked eye and fluorescence method. [ABSTRACT FROM AUTHOR]

Designed and synthesized a bis(salamo)-like fluorescent chemical sensor BS , which can be used as a highly selective and sensitive fluorescent probe for HCO 3 – and CO 3 2– detection. The sensing mechanism was investigated and the application of the sensor in practice was explored. In the field of ion detection, salamo-like chemical sensors have been less studied compared to other sensor molecules, especially for the recognition and detection of anions. Therefore, this study will to some extent contribute to expanding the application of salamo-like compounds. [Display omitted] • A bis(salamo)-like fluorescent sensor BS was designed and synthesized. • Sensor BS enables selective identification of HCO 3 – and CO 3 2– based on "turn-on" fluorescence. • Sensor BS is capable of being loaded on portable test strips for the practical testing of HCO 3 – and CO 3 2–. In this work, we successfully designed and synthesized a methoxydisubstituted bis(salamo)-type fluorescent chemical sensor BS , which can be applied as a highly sensitive and selective fluorescence probe for HCO 3 – and CO 3 2– detection. The LODs of HCO 3 – and CO 3 2– were experimentally calculated to be 5.4068 × 10−8 M and 4.4517 × 10−8 M, respectively. After relevant experiments, the sensing mechanism was investigated. Moreover, the application of the sensor in practice is explored, and the sensor BS can be loaded on portable test strips for ion detection. In the field of ion detection, salamo-like chemical sensors have been less studied compared to other sensor molecules, especially for the recognition and detection of anions. Therefore, this study will to some extent contribute to expanding the application of salamo-like compounds. [ABSTRACT FROM AUTHOR]

A new naphthalenediol-based bis(salamo)-type fluorescent probe H 4 L for Zn2+ and CN− was reported. Probe H 4 L showed a highly selective fluorescence enhancement toward Zn2+ over other metal ions including Cd2+, and obtained the L-Zn 2+ complex can only detect CN− in various anions. Their recognition mechanisms were explained by Job plots, fluorescent and UV–vis titrations, and theoretical calculations. The L-Zn 2+ complex has been synthesized and structurally characterized using Hirshfeld surface analysis, elemental analyses, IR, UV–Vis and fluorescent spectra. Additionally, the relay probe with the wide adaptability of pH range and excellent stability showed highly selectivity for CN− recognition. A new naphthalenediol-based bis(salamo)-type fluorescent probe H 4 L was reported, H 4 L showed a highly selective fluorescence enhancement toward Zn2+ over other metal ions including Cd2+, and obtained the L-Zn 2+ complex can only detect CN− in various anions. Unlabelled Image • A highly selective and sensitive fluorescent probe H 4 L for Zn2+ and CN− was synthesized. • The L-Zn 2+ complex has been synthesized and characterized structurally. • Recognition mechanism for Zn2+ was supported by theoretical calculations. [ABSTRACT FROM AUTHOR]