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Objective: To study the effect of pentoxifylline versus placebo on venous leg ulcers with and without compression therapy. Methods and Methodology: Prospective study of factorial design, permitting the simultaneous evaluation of alternative pharmaceutical, bandaging, and dressings materials. The study took place at the Department of General Surgery, I.G.I.M.S., Patna. A total of 40 patients with confirmed venous ulcers were included, after excluding other major causal factors. Participants were randomly assigned to receive either pentoxifylline or placebo. The main outcome measure was the complete healing (full epithelialization) of all ulcers on the study leg. Results: Among the patients receiving placebo, 10 out of 19 (53%) achieved complete healing, while among those receiving pentoxifylline, 14 out of 21 (64%) achieved complete healing. Conclusions: The study found no significant difference in healing rates between patients taking pentoxifylline and those receiving placebo. Recommendation: It is compression therapy that heals the ulcer, not the dressing, so wherever possible the primary dressing of choice should be a simple knitted viscose one. This recommendation may not apply if the wound has high levels of exudate or slough.

Background: Emergency hernia repair is technically very challenging and involves a very high risk of post-operative infectious complications in case of incarcerated incisional hernias in association with bowel obstruction which is due to its edematous, inflammatory, and friable tissues. The study's prime objective was to prospectively assess the wound-related morbidity in using permanent prosthetic mesh in an emergency laparotomy of an incarcerated incisional hernia with a corresponding intestinal obstruction. We also go over a novel method of leaving the mesh exposed for the formation of granulation tissue. Methods: Emergency laparotomy was performed on sixty patients with incarcerated incisional hernias associated with intestinal obstructions to place the permanent prosthetic mesh. In fifty-three patients hernia was repaired and the wound was sutured, but in seven individuals, it was left open to granulate. Results: 9 patients had superficial surgical site infections, 3 had deep wound infections, and 2 patients suffered from cellulitis which was seen in the group of patients where the wound was closed primarily. These patients underwent both wound debridement and antibiotics were administered. 2 patients required the removal of the mesh placed. In the group of patients who had their surgical wounds left exposed, there were no infections. On the 7th postoperative day, a patient in this group passed away from septicemia. Conclusion: In obstructed incisional hernia patient who was treated in emergency with permanent prosthetic mesh the wound infection was quite high on a contaminated field.

Background: In the present scenario the entire healthcare system has been overburdened with chronic wounds be it monetary wise or manpower requirements like nurses, doctors, etc. A chronic wound is being treated by many topical drugs which are prevailing in the market. So we considered this study i.e. “the effect of cadexomer and providone iodine on chronic leg ulcers”. Objective: The main and primary objective of this study was to compare the outcome of both, Cadexomer and povidone-iodine, about their effect on the treatment of leg ulcers. Methods: With 30 patients in each group, 30 patients with chronic wounds participated in this prospective study. As part of the statistical analysis, Pearson's Correlation Coefficient and the Student's Paired T-Test are used. Results: Patients who received cadexomer iodine ointment had a significantly (p