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Start Over Author "Prins, Judith B." Journal supportive care in cancer
17 results on '"Prins, Judith B."'

2. Cancer worry among BRCA1/2 pathogenic variant carriers choosing surgery to prevent tubal/ovarian cancer: course over time and associated factors

Author

van Bommel, Majke H. D., Steenbeek, Miranda P., IntHout, Joanna, Hermens, Rosella P. M. G., Hoogerbrugge, Nicoline, Harmsen, Marline G., van Doorn, Helena C., Mourits, Marian J. E., van Beurden, Marc, Zweemer, Ronald P., Gaarenstroom, Katja N., Slangen, Brigitte F. M., Brood-van Zanten, Monique M. A., Vos, M. Caroline, Piek, Jurgen M., van Lonkhuijzen, Luc R. C. W., Apperloo, Mirjam J. A., Coppus, Sjors F. P. J., Prins, Judith B., Custers, José A. E., and de Hullu, Joanne A.

Published
2022
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13. Prevalence and correlates of high fear of cancer recurrence in late adolescents and young adults consulting a specialist adolescent and young adult (AYA) cancer service

Author

Thewes, Belinda, primary, Kaal, Suzanne E. J., additional, Custers, Jose A. E., additional, Manten-Horst, Eveliene, additional, Jansen, Rosemarie, additional, Servaes, Petra, additional, van der Graaf, Winette T. A., additional, Prins, Judith B., additional, and Husson, Olga, additional

Published
2017
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14. Quality of life of patients with locally advanced head and neck cancer treated with induction chemotherapy followed by cisplatin-containing chemoradiotherapy in the Dutch CONDOR study: a randomized controlled trial.

Author

Driessen, Chantal M L, Groenewoud, Johannes M M, de Boer, Jan Paul, Gelderblom, Hans, van der Graaf, Winette T A, Prins, Judith B, Kaanders, Johannes H A M, and van Herpen, Carla M L

Subjects
ANTINEOPLASTIC agents, CISPLATIN, CLINICAL trials, COMPARATIVE studies, FLUOROURACIL, HEAD tumors, RESEARCH methodology, MEDICAL cooperation, NECK tumors, QUALITY of life, RESEARCH, RESEARCH funding, PILOT projects, EVALUATION research, RANDOMIZED controlled trials
Abstract

Purpose: The CONDOR study showed that docetaxel/cisplatin/5-fluorouracil (TPF) followed by conventional radiotherapy with cisplatin 100 mg/m2 on days 1, 22, and 43 (cis100 + RT; n = 27)) versus accelerated radiotherapy with cisplatin weekly 40 mg/m2 (cis40 + ART; n = 29) in locally advanced head and neck cancer (LAHNC) patients was not feasible. Here, we report the analysis of health-related quality of life (HRQOL) of the patients entered in this study.Methods: HRQOL was assessed at baseline, after two TPF, before start of chemoradiotherapy, and 1, 4, 8, 12, and 24 months after completion of chemoradiotherapy using the EORTC-QLQ-C30 and QLQ-H&N35 in 62 patients.Results: Compliance with the QOL questionnaires was 94% (59/62) at baseline and 61% (30/49) at 12 months, respectively. HRQOL decreased after TPF and further decreased during chemoradiohteray in both arms equally. Pain and swallowing dysfunction improved significantly during TPF but deteriorated below baseline levels during chemoradiotherapy, cis40 + ART > cis100 + RT (p < 0.05). HRQOL and symptoms restored to baseline within 12 months in both arms and remained at that level until 24 months.Conclusions: After TPF, cis40 + ART had a larger negative impact on symptoms than cis100 + RT, probably due to the ART. HRQOL and symptoms restored to baseline levels within 12 months after end of treatment in both arms, which is an important perspective for patients during the phase of most serious acute side effects of treatment.Trial Registration: NCT00774319. [ABSTRACT FROM AUTHOR]

Published
2018
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