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data base (7F, mean age 457y, BMI 518 kg/m 2 , HbA1c: 8.31%). 16 LRYGB Obese Diabetics with similar pre-operative features (Group2), were identified (7F; mean age 458y; BMI 484 kg/m2, HbA1c: 8.51%). LRGBP alimentary limb was 150 cm and bilio-pancreatic limb was 50 cm from Treitz ligament. SG vertical transection was calibrated on a 40F oro-gastric bougie. Data were analyzed at 15 days, 6 months, 1 year according weight loss and diabetes resolution (fasting glucose 126 mg/dl without hypoglycemic drugs). Data were reported as meanSD, statistical analysis was by Fisher’s exact test (p0.05 was significant). Results: Group1 and Group2 BMI were comparable at 15 days: 467 and 445 kg/m2, respectively (p0,479). BMI was significantly lower in Group2 (354 and 325 kg/m 2 ) vs. Group 1 (426 and 385 kg/m 2 ) at 6 months and 1 year respectively (P0.02). Diabetes resolution occurred in 66, 77and 77% of Group1 patients and in 94, 100, 94% of Group2 at 15 days, 6 months and 1 year, respectively (pns). Conclusion: In spite of its statistically significant inferiority regarding weight loss in comparison with LRYGB, SG is equally effective for the diabetes resolution.