1. Efficacy and safety of salvage endoscopy in the treatment of residual or recurrent colorectal neoplasia after endoscopic resection: a systematic review and meta-analysis.
- Author
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Du, Juan, Zhang, Ting, Wang, Lei, Zhang, Hao, and Yi, Wenquan
- Subjects
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MEDICAL information storage & retrieval systems , *CANCER relapse , *PATIENT safety , *COLORECTAL cancer , *ENDOSCOPIC surgery , *TREATMENT effectiveness , *META-analysis , *SURGICAL blood loss , *SURGICAL therapeutics , *SYSTEMATIC reviews , *MEDLINE , *MEDICAL databases , *ONLINE information services , *CONFIDENCE intervals , *POSTOPERATIVE period , *ENDOSCOPY , *EVALUATION - Abstract
Objective: To systematically review and meta-analyze the efficacy and safety of salvage endoscopy for residual or recurrence of colorectal tumors after endoscopic resection. Methods: Multiple databases including PubMed, EMBASE and the Cochrane Library were searched to screen for eligible studies and perform data extraction and pooled analysis. Results: Sixteen studies on salvage endoscopy for residual or recurrent colorectal cancer after endoscopic resection were included, covering approximately 994 patients. The results of the meta-analysis demonstrated that salvage endoscopic therapy for residual or recurrent colorectal tumors following endoscopic resection achieved an en bloc resection rate of 92% (95% CI 0.85–0.97; I2 = 91%) and an R0 resection rate of 82% (95% CI 0.75–0.87; I2 = 78%). The rates of intraoperative or postoperative bleeding and perforation were 10%/1% and 5%/2%, and the recurrence rate was 2%. Conclusions: Salvage endoscopic resection is an effective and safe treatment strategy for residual or recurrent colorectal tumors after endoscopic resection. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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