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Managing ambiguous and asymmetric types of information is a very challenging task under the consideration of classical data. Furthermore, Aczel-Alsina aggregation operators are the new developments in fuzzy sets theory. However, when decision-makers need to use these structures in fuzzy rough structures, these operators fail to deal with such types of values, as fuzzy rough structures use lower and upper approximation spaces. Thus, an encasement of an intuitionistic fuzzy set has a chance of data loss, whereas an intuitionistic fuzzy rough set can resolve the problem of data loss. Motivated by the notion of intuitionistic fuzzy rough sets and new aggregation operators i.e., intuitionistic fuzzy Aczel-Alsina operators, this paper firstly initiates some basic Aczel-Alsina operational rules for intuitionistic fuzzy rough numbers. Secondly, based on these newly defined operational rules, we have developed some new aggregation operators, such as intuitionistic fuzzy rough Aczel-Alsina weighted average (IFRAAWA), intuitionistic fuzzy rough Aczel-Alsina ordered weighted average (IFRAAOWA), and intuitionistic fuzzy rough Aczel-Alsina hybrid average (IFRAAHA) aggregation operators. Moreover, the properties of these aggregation operators have been initiated. These operators can help in evaluating awkward and asymmetric information in real-life problems. The use of aggregation operators in medical diagnosis and MADM is an efficient method that can help in healthcare and decision-making applications. To present an effective use of these developed operators in medical diagnosis and the selection of the best next-generation firewall, we have established an algorithm along with a numerical example to provide authenticity and clarity to the established work. Furthermore, a comparative analysis of the introduced work shows the superiority of the introduced approach. [ABSTRACT FROM AUTHOR]

Due to false negative results of the real-time Reverse Transcriptase-Polymerase Chain Reaction (RT-PCR) test, the complemental practices such as computed tomography (CT) and X-ray in combination with RT-PCR are discussed to achieve a more accurate diagnosis of COVID-19 in clinical practice. Since radiology includes visual understanding as well as decision making under limited conditions such as uncertainty, urgency, patient burden, and hospital facilities, mistakes are inevitable. Therefore, there is an immediate requirement to carry out further investigation and develop new accurate detection and identification methods to provide automatically quantitative evaluation of COVID-19. In this paper, we propose a new computer-aided diagnosis application for COVID-19 detection using deep learning techniques. A new technique, which receives symmetric X-ray data as the input, is presented in this study by combining Convolutional Neural Networks (CNN) with Ant Lion Optimization Algorithm (ALO) and Multiclass Naïve Bayes Classifier (NB). Moreover, several other classifiers such as Softmax, Support Vector Machines (SVM), K-Nearest Neighbors (KNN) and Decision Tree (DT) are combined with CNN. The promising results of these classifiers are evaluated and presented for accuracy, precision, and F1-score metrics. NB classifier with Ant Lion Optimization Algorithm and CNN produced the best results with 98.31% accuracy, 100% precision and 98.25% F1-score and with the lowest execution time. [ABSTRACT FROM AUTHOR]

This paper proposes a simple and effective retinal fundus image simulation modeling to enhance contrast and adjust the color balance for symmetric information in biomedicine. The aim of the study is for reliable diagnosis of AMD (age-related macular degeneration) screening. The method consists of a few simple steps. Firstly, local image contrast is refined with the CLAHE (Contrast Limited Adaptive Histogram Equalization) technique by operating CIE L*a*b* color space. Then, the contrast-enhanced image is stretched and rescaled by a histogram scaling equation to adjust the overall brightness offsets of the image and standardize it to Hubbard's retinal image brightness range. The proposed method was assessed with retinal images from the DiaretDB0 and STARE datasets. The findings in the experimentation section indicate that the proposed method results in delightful color naturalness along with a standard color of retinal lesions. [ABSTRACT FROM AUTHOR]

Although hepatitis B is widespread, it is hard to cure. This paper presents a new and more accurate model for the diagnosis and treatment of hepatitis B. Based on previous research, the diagnosis and treatment modes were combined into one. By adding more influencing factors and risk factors, the overall diagnosis and treatment model will be further expanded, and a richer and more detailed overall diagnosis and treatment model will be constructed. Reverse logic gates are used in the model to improve the accuracy of the treatment planning. The new unified model is more accurate in subdividing diagnosis results, and it is more flexible and accurate in providing dynamic treatment plans. The prediction process and the static diagnosis process of the model are symmetric, and the related sub-graph is symmetric in structure. In addition, an algorithm for predicting the response probability of treatment scheme is developed, so as to predict the subsequent treatment effects of the current treatment scheme, such as the probability of drug resistance. The results show that this method is more accurate than other available systems, and it has encouraging diagnostic accuracy and effectiveness, which provides a promising help for doctors in diagnosing hepatitis B. [ABSTRACT FROM AUTHOR]

One of the most prevalent cancers in women is breast cancer. The mortality rate related to this disease can be decreased by early, accurate diagnosis to increase the chance of survival. Infrared thermal imaging is one of the breast imaging modalities in which the temperature of the breast tissue is measured using a screening tool. The previous studies did not use pre-trained deep learning (DL) with deep attention mechanisms (AMs) on thermographic images for breast cancer diagnosis. Using thermal images from the Database for Research Mastology with Infrared Image (DMR-IR), the study investigates the use of a pre-trained Visual Geometry Group with 16 layers (VGG16) with AMs that can produce good diagnosis performance utilizing the thermal images of breast cancer. The symmetry of the three models resulting from the combination of VGG16 with three types of AMs is evident in all its stages in methodology. The models were compared to state-of-art breast cancer diagnosis approaches and tested for accuracy, sensitivity, specificity, precision, F1-score, AUC score, and Cohen's kappa. The test accuracy rates for the AMs using the VGG16 model on the breast thermal dataset were encouraging, at 99.80%, 99.49%, and 99.32%. Test accuracy for VGG16 without AMs was 99.18%, whereas test accuracy for VGG16 with AMs improved by 0.62%. The proposed approaches also performed better than previous approaches examined in the related studies. [ABSTRACT FROM AUTHOR]

Diagnosis is a measurement, and so is intelligence. We present a novel visual method to analyze diagnoses. The concept of country health was introduced in a trial to compare the efficiency of two treatments: box plot and pull anti. We found that the pull anti performs better in both accuracy and extent. The box plot is a diagnosis of abnormality using simple up–down symmetry; however, when abnormalities occur in the probability, the symmetry of the structure may be negatively affected. The pull anti checks the asymmetry of the left and right and therefore results in a better analysis. Furthermore, we designed another trial to test the sampling bias and found that an insensible disturbance might lead to statistical self-significance. We thus suggest that extended observations towards certainty are necessary to obtain better diagnoses or intelligence. [ABSTRACT FROM AUTHOR]

Accurate segmentation of retinal blood vessels is a key step in the diagnosis of fundus diseases, among which cataracts, glaucoma, and diabetic retinopathy (DR) are the main diseases that cause blindness. Most segmentation methods based on deep convolutional neural networks can effectively extract features. However, convolution and pooling operations also filter out some useful information, and the final segmented retinal vessels have problems such as low classification accuracy. In this paper, we propose a multi-scale residual attention network called MRA-UNet. Multi-scale inputs enable the network to learn features at different scales, which increases the robustness of the network. In the encoding phase, we reduce the negative influence of the background and eliminate noise by using the residual attention module. We use the bottom reconstruction module to aggregate the feature information under different receptive fields, so that the model can extract the information of different thicknesses of blood vessels. Finally, the spatial activation module is used to process the up-sampled image to further increase the difference between blood vessels and background, which promotes the recovery of small blood vessels at the edges. Our method was verified on the DRIVE, CHASE, and STARE datasets. Respectively, the segmentation accuracy rates reached 96.98%, 97.58%, and 97.63%; the specificity reached 98.28%, 98.54%, and 98.73%; and the F-measure scores reached 82.93%, 81.27%, and 84.22%. We compared the experimental results with some state-of-art methods, such as U-Net, R2U-Net, and AG-UNet in terms of accuracy, sensitivity, specificity, F-measure, and AUC R O C . Particularly, MRA-UNet outperformed U-Net by 1.51%, 3.44%, and 0.49% on DRIVE, CHASE, and STARE datasets, respectively. [ABSTRACT FROM AUTHOR]

Accurate brain tumor segmentation from 3D Magnetic Resonance Imaging (3D-MRI) is an important method for obtaining information required for diagnosis and disease therapy planning. Variation in the brain tumor's size, structure, and form is one of the main challenges in tumor segmentation, and selecting the initial contour plays a significant role in reducing the segmentation error and the number of iterations in the level set method. To overcome this issue, this paper suggests a two-step dragonfly algorithm (DA) clustering technique to extract initial contour points accurately. The brain is extracted from the head in the preprocessing step, then tumor edges are extracted using the two-step DA, and these extracted edges are used as an initial contour for the MRI sequence. Lastly, the tumor region is extracted from all volume slices using a level set segmentation method. The results of applying the proposed technique on 3D-MRI images from the multimodal brain tumor segmentation challenge (BRATS) 2017 dataset show that the proposed method for brain tumor segmentation is comparable to the state-of-the-art methods. [ABSTRACT FROM AUTHOR]

The T-Spherical fuzzy set (TSFS) is the most generalized form among the introduced fuzzy frameworks. It obtains maximum information from real-life phenomena due to its maximum range. Consequently, TSFS is a very useful structure for dealing with information uncertainties, especially when human opinion is involved. The correlation coefficient (CC) is a valuable tool, possessing symmetry, to determine the similarity degree between objects under uncertainties. This research aims to develop a new CC for TSFS to overcome the drawbacks of existing methods. The proposed CCs are generalized, flexible, and can handle uncertain situations where information has more than one aspect. In addition, the proposed CCs provide decision-makers independence in establishing their opinion. Based on some remarks, the usefulness of the new CC is reviewed, and its generalizability is evaluated. Moreover, the developed new CC is applied to pattern recognition for investment decisions and medical diagnosis of real-life problems to observe their effectiveness and applicability. Finally, the validity of the presented CC is tested by comparing it with the results of the previously developed CC. [ABSTRACT FROM AUTHOR]

Cut sets, decomposition theorem and representation theorem have a great influence on the realization of the transformation of fuzzy sets and classical sets, and the single-valued neutrosophic multisets (SVNMSs) as the generalization of fuzzy sets, which cut sets, decomposition theorem and representation theorem have the similar effects, so they need to be studied in depth. In this paper, the decomposition theorem, representation theorem and the application of a new similarity measures of SVNMSs are studied by using theoretical analysis and calculations. The following are the main results: (1) The notions, operation and operational properties of the cut sets and strong cut sets of SVNMSs are introduced and discussed; (2) The decomposition theorem and representation theorem of SVNMSs are established and rigorously proved. The decomposition theorem and the representation theorem of SVNMSs are the theoretical basis for the development of SVNMSs. The decomposition theorem provides a new idea for solving the problem of SVNMSs, and points out the direction for the principle of expansion of SVNMSs. (3) Based on the decomposition theorem and representation theorem of SVNMSs, a new notion of similarity measure of SVNMSs is proposed by applying triple integral. And this new similarity is applied to the practical problem of multicriteria decision-making, which explains the efficacy and practicability of this decision-making method. The new similarity is not only a way to solve the problem of multi-attribute decision-making, but also contains an important mathematical idea, that is, the idea of transformation. [ABSTRACT FROM AUTHOR]

In this paper, a novel similarity measure for interval-valued intuitionistic fuzzy sets is introduced, which is based on the transformed interval-valued intuitionistic triangle fuzzy numbers. Its superiority is shown by comparing the proposed similarity measure with some existing similarity measures by some numerical examples. Furthermore, the proposed similarity measure is applied to deal with pattern recognition and medical diagnosis problems. [ABSTRACT FROM AUTHOR]

In the sequential three-way decision model (S3WD), conditional probability and decision threshold pair are two key elements affecting the classification results. The classical model calculates the conditional probability based on the strict equivalence relationship, which limits its application in reality. In addition, little research has studied the relationship between the threshold change and its cause at different granularity levels. To deal with these deficiencies, we propose a novel sequential three-way decision model and apply it to medical diagnosis. Firstly, we propose two methods of calculating conditional probability based on similarity relation, which satisfies the property of symmetry. Then, we construct an S3WD model for a medical information system and use three different kinds of cost functions as the basis for modifying the threshold pair at each level. Subsequently, the rule of the decision threshold pair change is explored. Furthermore, two algorithms used for implementing the proposed S3WD model are introduced. Finally, extensive experiments are carried out to validate the feasibility and effectiveness of the proposed model, and the results show that the model can achieve better classification performance. [ABSTRACT FROM AUTHOR]

The cubic q-rung orthopair hesitant fuzzy set (Cq-ROHFS) provides greater information and is capable of representing both the interval-valued q-rung orthopair hesitant fuzzy set (IVq-ROHFS) and the q-rung orthopair hesitant fuzzy set (q-ROHFS). The concept of Cq-ROHFS is more flexible when considering the symmetry between two or more objects. In social life, complex decision information is often too uncertain and hesitant to allow precision. The cubic q-rung orthopair hesitant fuzzy sets are a useful tool for representing uncertain and hesitant fuzzy information in uncertain decision situations. Using the least common multiple (LCM) extension method, we propose a decision-making method based on an exponential similarity measure and hesitancy in the cubic q-rung orthopair hesitant fuzzy environment. To represent assessment information more accurately, our proposed method adjusts parameters according to the decision maker's preferences in the decision-making process. The Cq-ROHFS setting was used to develop a depression rating method based on the similarity measure for depressed patients. Finally, the validity and applicability of the decision method is demonstrated using an example of depression rating assessment. As a result of this study, the scientific community can gain insight into real-world clinical diagnostic problems and treatment options. [ABSTRACT FROM AUTHOR]

In this article, a new hybrid model named linear Diophantine fuzzy rough set (LDFRS) is proposed to magnify the notion of rough set (RS) and linear Diophantine fuzzy set (LDFS). Concerning the proposed model of LDFRS, it is more efficient to discuss the fuzziness and roughness in terms of linear Diophantine fuzzy approximation spaces (LDFA spaces); it plays a vital role in information analysis, data analysis, and computational intelligence. The concept of (< p , p ′ > , < q , q ′ >) -indiscernibility of a linear Diophantine fuzzy relation (LDF relation) is used for the construction of an LDFRS. Certain properties of LDFA spaces are explored and related results are developed. Moreover, a decision-making technique is developed for modeling uncertainties in decision-making (DM) problems and a practical application of fuzziness and roughness of the proposed model is established for medical diagnosis. [ABSTRACT FROM AUTHOR]

Facial asymmetry refers to the absence of, or the deviation from the regular mirror image of facial structures, relative to a referenced midline axis. It can be attributed to a wide spectrum of deformities, including congenital, developmental, or acquired conditions, which can originate either prenatally or postnatally. Though highly prevalent, asymmetry commonly goes undiagnosed due to its subtle or relative nature. Among the spectrum of conditions, acquired cases are triggered postnatally, in previously normal individuals, thus subjecting them to sudden, eventful psychological and psychosocial disharmony. When detected early, timely management may help intervene progressive growth of these conditions. This, therefore, emphasizes the need for a thorough diagnostic workup including medical/dental history, clinical examinations, study models, photographic and radiographic records for a case-by-case basis to prevent severe functional and aesthetic complications. Recently, advanced diagnostic procedures, such as stereophotogrammetry, 3D stereolithographic models, skeletal scintigraphy (radionucleotide scans), 3D computed tomographic scans, cone-beam computed tomography, and magnetic resonance imaging, have provided innovative diagnostic instruments for numerous craniofacial defects. This descriptive review aims at focusing on the factors leading to frequently encountered conditions of acquired facial asymmetry and highlights their clinical evaluation, conservative and surgical interventions by a multi-disciplinary team of clinicians. [ABSTRACT FROM AUTHOR]

Infections can be triggered by a wide range of pathogens. However, there are few strains of bacteria that cause illness, but some are quite life-threatening. Likewise, viral infections are responsible for many human diseases, usually characterized by high contagiousness. Hence, as bacterial and viral infections can both cause similar symptoms, it can be difficult to determine the exact cause of a specific infection, and this limitation is critical. However, recent scientific advances have geared us up with the proper tools required for better diagnoses. Recent discoveries have confirmed the involvement of non-coding RNAs (ncRNAs) in regulating the pathogenesis of certain bacterial or viral infections. Moreover, the presence of reactive oxygen species (ROS) is also known as a common infection trait that can be used to achieve a more complete description of such pathogen-driven conditions. Thus, this opens further research opportunities, allowing scientists to explore infection-associated genetic patterns and develop better diagnosis and treatment methods. Therefore, the aim of this review is to summarize the current knowledge of the implication of ncRNAs and ROS in bacterial and viral infections, with great emphasis on their symmetry but, also, on their main differences. [ABSTRACT FROM AUTHOR]

Congestive heart failure (CHF) poses a serious threat to human health. Once the diagnosis of CHF is established, clinical experts need to assess the severity of CHF in a timely manner. It is proved that electrocardiogram (ECG) signals are useful for assessing the severity of CHF. However, since the ECG perturbations are subtle, it is difficult for doctors to detect the differences of ECGs. In order to help doctors to make an accurate diagnosis, we proposed a novel multi-scale residual network (ResNet) to automatically classify CHF into four classifications according to the New York Heart Association (NYHA) functional classification system. Furthermore, in order to make the reported results more realistic, we used an inter-patient paradigm to divide the dataset, and segmented the ECG signals into two different intervals. The experimental results show that the proposed multi-scale ResNet-34 has achieved an average positive predictive value, sensitivity and accuracy of 93.49%, 93.44% and 93.60% respectively for two seconds of ECG segments. We have also obtained an average positive predictive value, sensitivity and accuracy of 94.16%, 93.79% and 94.29% respectively for five seconds of ECG segments. The proposed method can be used as an auxiliary tool to help doctors to classify CHF. [ABSTRACT FROM AUTHOR]

Fuzzy graph models enjoy the ubiquity of being in natural and human-made structures, namely dynamic process in physical, biological and social systems. As a result of inconsistent and indeterminate information inherent in real-life problems which are often uncertain, it is highly difficult for an expert to model those problems based on a fuzzy graph (FG). Vague graph structure (VGS) can deal with the uncertainty associated with the inconsistent and indeterminate information of any real-world problem, where fuzzy graphs may fail to reveal satisfactory results. Likewise, VGSs are very useful tools for the study of different domains of computer science such as networking, capturing the image, clustering, and also other issues like bioscience, medical science, and traffic plan. The limitations of past definitions in fuzzy graphs have led us to present new definitions in VGSs. Operations are conveniently used in many combinatorial applications. In various situations, they present a suitable construction means; therefore, in this research, three new operations on VGSs, namely, maximal product, rejection, residue product were presented, and some results concerning their degrees and total degrees were introduced. Irregularity definitions have been of high significance in the network heterogeneity study, which have implications in networks found across biology, ecology and economy; so special concepts of irregular VGSs with several key properties were explained. Today one of the most important applications of decision making is in medical science for diagnosing the patient's disease. Hence, we recommend an application of VGS in medical diagnosis. [ABSTRACT FROM AUTHOR]

Our purpose is to develop the preoperative diagnosis stage for orthopedic surgical treatments using additive manufacturing technology. Our methods involve fast implementations of an additive manufactured bone model, converted from CAT data, through appropriate software use. Then, additive manufacturing of the formed surfaces through special 3D-printers. With the structural model redesigned and printed in three dimensions, the surgeon is able to look at the printed bone and he can handle it because the model perfectly reproduces the real one upon which he will operate. We found that additive manufacturing models can precisely characterize the anatomical structures of fractures or lesions. The studied practice helps the surgeon to provide a complete preoperative valuation and a correct surgery, with minimized duration and risks. This structural model is also an effective device for communication between doctor and patient. [ABSTRACT FROM AUTHOR]

Glaucoma is a group of eye diseases which can cause vision loss by damaging the optic nerve. Early glaucoma detection is key to preventing vision loss yet there is a lack of noticeable early symptoms. Colour fundus photography allows the optic disc (OD) to be examined to diagnose glaucoma. Typically, this is done by measuring the vertical cup-to-disc ratio (CDR); however, glaucoma is characterised by thinning of the rim asymmetrically in the inferior-superior-temporal-nasal regions in increasing order. Automatic delineation of the OD features has potential to improve glaucoma management by allowing for this asymmetry to be considered in the measurements. Here, we propose a new deep-learning-based method to segment the OD and optic cup (OC). The core of the proposed method is DenseNet with a fully-convolutional network, whose symmetric U-shaped architecture allows pixel-wise classification. The predicted OD and OC boundaries are then used to estimate the CDR on two axes for glaucoma diagnosis. We assess the proposed method’s performance using a large retinal colour fundus dataset, outperforming state-of-the-art segmentation methods. Furthermore, we generalise our method to segment four fundus datasets from different devices without further training, outperforming the state-of-the-art on two and achieving comparable results on the remaining two. [ABSTRACT FROM AUTHOR]