1. Direct C-H Arylation of Quinones with Anilines.
- Author
-
Lamblin, Marc, Naturale, Guillaume, Dessolin, Jean, and Felpin, François-Xavier
- Subjects
- *
ARYLATION , *QUINONE , *ANILINE , *COUPLING reactions (Chemistry) , *BENZOQUINONES , *NITRITES , *DIAZONIUM compounds - Abstract
We discovered that anilines were suitable for the direct C-H arylation of benzoquinone in the presence of tert-butyl nitrite. This new reaction proceeds through the in situ formation of a diazonium hydroxide species. The coupling can be carried out at room temperature under neutral, additive-free, metal-free, and aqueous conditions, allowing an environmentally friendly procedure. [ABSTRACT FROM AUTHOR]
- Published
- 2012
- Full Text
- View/download PDF