Search

Summary Objective The purpose of this study was to examine the influence of leptin in women with uterine myoma. Materials and Methods In this study, 38 women with myoma uteri and 30 normal women who applied to the Dr Zekai Tahir Burak Woman Health Research and Education Hospital's gynecology clinic were enrolled. Uterine leiomyomas were proved by pathology postoperatively. In all subjects, FSH, LH, E2, prolactin, hemoglobin, hematocrit, blood urea nitrogen, creatinine, fasting glucose, CA125, and leptin were examined, and body mass index (BMI) was calculated. Data were analyzed by Student's t test and Mann-Whitney U test. Results Although leptin level was higher in the myomatic women (5.73 ± 4.08 ng/mL) than in the normal women, there was no statistically significant difference ( p = 0.303). Also, no statistical difference in the ratios of leptin/BMI was found in both groups. A significant correlation was found between high E2 level and myoma uteri ( p = 0.021). Hemoglobin levels were significantly lower in the myomatic women ( p = 0.044). When we compared the leptin levels according to BMI, leptin levels were higher in patients who had BMI > 30 ( p = 0.02). Conclusion We did not find any significant difference in serum leptin levels between the two groups. But leptin may have an indirect role in the pathogenesis of uterine leiomyoma. So further research is needed to reveal the role of leptin in myoma uteri pathogenesis.

Summary Objective We report a case of alveolar soft part sarcoma (ASPS) of the tongue that presented in the third trimester of pregnancy. Case Report An 18-year-old, gravida 1, para 0, woman with ASPS of the tongue in the 31 st week of pregnancy was described. Approximately 4 months after her first diagnosis, she was referred to our clinic for the delivery of her baby and additional treatment. At 32 weeks of gestation, a healthy male infant weighing 2,220 g was delivered by cesarean section. After an uneventful postoperative course, she was referred to the Department of otorhinolaryngology and maxillofacial surgery for further investigation and treatment. Conclusion ASPS ofthe tongue presenting in pregnancy is an extremely rare combination, and to our knowledge, this is the first reported case in the English literature. The diagnostic and therapeutic management ofthe pregnant patient with cancer, like ASPS, is especially difficult, because it involves both the mother and fetus. [ Taiwan J Obstet Gynecol 2008;47(2):21 2-21 4]