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In the aim of further research of the highly bioactive benzofuran and triazine derivatives, the synthesis of 1,2,4-triazine derivatives bearing the benzofuran moiety has been undertaken. Using a simple and convenient method, a three steps synthesis of novel functionalized 1,2,4-triazine derivatives from readily available starting materials has been described. Herein, two derivatives of 1,2,4-triazine were obtained in moderate yields. The structures of all synthesized compounds were elucidated by spectral methods of analysis

In the further research and synthesis of hybrid molecules which exhibit highly biological activities, the synthesis of triazole-fused bicyclic heterocycles bearing the benzofuran has been undertaken. A facile, convenient and good yielding synthesis of novel benzofuran-bearing 1,2,4-trazole derivatives were described. Herein, two derivatives of [1,2,4]triazolo[3,4-b][1,3,4]thiadiazole were synthesized from salicylaldehyde in four steps in moderate to good yields. Structures of all the targeted synthesized compounds were elucidated by spectral methods of analysis

Miliusa velutina Dun Hook. f. et. Thoms is the rare and native plant, belongs to the Annonaceae family. The isolated compounds in Miliusa genus showed that many function groups and have diverse bioactivities from the ethyl acetate extract of the trunk of Miliusa velutina, three compounds were isolated and determined based on 1D, 2D NMR spectra, MS and combined comparison with references. The three structurally defined compounds are: 4-hydroxybenzoic acid (1), p-coumaric acid (2), 1-O-methyl- -D-glucopyranoside (3). All of three compounds are first known to exist in the Miliusa velutina.