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The Lhasa terrane of the southern Tibetan Plateau participated in a Mesozoic Andean-type orogeny caused by the northward subduction of the Neo-Tethyan oceanic lithosphere. However, metamorphic rocks, which can unravel details of the geodynamic evolution, are rare and only exposed in the south-eastern part of the Lhasa terrane. Therefore, we conducted a detailed petrological, geochemical and U–Pb zircon geochronological study of the late Cretaceous metamorphic rocks and associated gabbros from the Nyemo inlier of the southern Lhasa terrane. The Nyemo metamorphic rocks including gneisses, schists, marbles and calc-silicate rocks, experienced peak amphibolite-facies contact metamorphism under P–T conditions of 3.5–4.0 kbar and 642–657 °C with a very high geothermal gradient of 45–50 °C/km, revealing a distinct deflection from the steady-state geotherm during low-pressure metamorphism. Inherited magmatic zircon cores from the metamorphic rocks yielded protolith ages of 197–194 Ma, while overgrowth zircon rims yielded metamorphic ages of ca. 86 Ma. Whole-rock chemistry and zircon Hf isotopes suggest that the protoliths of the gneisses and schists are andesites and tuffs of the early Jurassic Sangri Group, which were derived from a depleted mantle source of a continental arc affinity. The coeval intimately-associated gabbro (ca. 86 Ma) crystallized under P–T conditions of 3.5–5.3 kbar and 914–970 °C, supplying the heat flux high enough to cause the contact metamorphism of the Sangri Group rock types. We propose that the intrusion of the gabbro and a simultaneous pressure increase of up to 4.0 kbar, which is related to crustal thickening due to crustal overthrusting and the intrusion of mafic material, resulted in the late Cretaceous metamorphism of the early Jurassic Sangri Group during an Andean-type orogeny. Furthermore the Nyemo metamorphic rocks, which have previously been considered to represent slivers of the Precambrian metamorphic basement of the Lhasa terrane, are late Cretaceous metamorphic supracrustal rocks. [ABSTRACT FROM AUTHOR]