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An efficient method for the synthesis of polyfunctional imidazoles from vinyl azides and amidine has been developed. Starting from vinyl azide and amidine, this transformation proceeds without any additives and the obtained imidazoles can be decorated with ester functional group that is a promising site for further modification.

A simple and direct synthesis of 2-aminoimidazoles from vinyl azides and cyanamide was developed. An attractive feature of this protocol is that the desired products are generated in a highly efficient and eco-friendly manner without the use of a catalyst. A plausible mechanism has been proposed.

Simple and eco-friendly synthesis of polyfunctionalized 2-aminopyrroles from vinyl azides and α-cyano derivatives has been accomplished with a good to excellent yield. The reaction was performed in ethanol/water co-solvent system without catalyst and the workup was facile. A plausible mechanism has been proposed.

A novel and facile approach to polysubstituted pyrazoles from readily synthesized hydrazonyl chlorides and vinyl azides was developed. The reaction was regiospecific and proceeded under mild conditions in the presence of base.