1. Naphthalene dianhydride based selective detection targetable fluorescent probe for monitoring exogenous Iron in living cells.
- Author
-
Rohini, Gandhaveeti, Ramaiah, Konakanchi, and Sreekanth, Anandaram
- Subjects
- *
NAPHTHALENE , *HYDRIDES , *FLUORESCENT probes , *IRON , *METAL ions , *FLUORESCENCE spectroscopy , *CELL imaging - Abstract
Graphical abstract Highlights • Naphthalene dianhydride based novel probe R1 useful for the detection of Fe+3. • The performance of probe R1 over the other di/trivalent ions. • The PET mechanism on fluorescent turn-on cell permeable probe. • The efficacy of R1 towards live-cells. Abstract A green emissive PET operating fluorescent turn-on cell permeable novel probe R1 has been successfully developed and utilized for the detection of Fe+3 in the pure aqueous system at sub-nanomolar level. Moreover, probe R1 demonstrate highly sensitive and selective towards Fe+3 over the other divalent and trivalent metal ions and was established by using fluorescence spectroscopy. The efficiency and aid of R1 was demonstrated by the fluorescence imaging of captured Fe+3 within Pollen grains by using fluorescence microscopy. These results indicate that, this is the first fluorescent turn-on PET probe to detect sub-nanomolar Fe+3 in the pure aqueous system and in cellular level. [ABSTRACT FROM AUTHOR]
- Published
- 2018
- Full Text
- View/download PDF