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Your search keyword '"Rosenberg, Ivan"' showing total 2 results
Start Over Author "Rosenberg, Ivan" Journal tetrahedron letters: international organ for the rapid publication of preliminary communications in organic chemistry
2 results on '"Rosenberg, Ivan"'

1. Straightforward synthesis of 3′-deoxy-3′,4′-didehydronucleoside-5′-aldehydes via 2′,3′-O-orthoester group elimination: a simple route to 3′,4′-didehydronucleosides

Author

Petrová, Magdalena, Buděšínský, Miloš, and Rosenberg, Ivan

Subjects
*ORGANIC synthesis, *ALDEHYDES, *DEOXYRIBONUCLEOTIDES, *NUCLEOSIDES, *RIBOSE, *ORGANIC chemistry
Abstract

Abstract: Straightforward, high-yielding syntheses of 3′-deoxy-3′,4′-didehydronucleoside-5′-aldehydes and 3′-deoxy-3′,4′-didehydronucleosides starting from 2′,3′-O-orthoester derivatives of ribonucleosides are described. [ABSTRACT FROM AUTHOR]

Published
2010
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2. Methyl 4-toluenesulfonyloxymethylphosphonate, a new and versatile reagent for the convenient synthesis of phosphonate-containing compounds

Author

Kóšiová, Ivana, Točík, Zdeněk, Buděšínský, Miloš, Šimák, Ondřej, Liboska, Radek, Rejman, Dominik, Pačes, Ondřej, and Rosenberg, Ivan

Subjects
*PHOSPHONATES, *CHEMICAL reagents, *CHROMATOGRAPHIC analysis, *ESTERS, *ORGANIC synthesis, *METHYLATION, *ALKYLATION
Abstract

Abstract: A straightforward procedure leading to the new phosphonylating reagent, methyl 4-toluenesulfonyloxymethylphosphonate, requiring no chromatographic purification is described. This stable reagent works with the same efficiency as dimethyl and other dialkyl esters for the introduction of an O-phosphonomethyl moiety while, in contrast to dimethyl ester, it does not cause any unwanted methylation of sensitive functionalities. Its utility for the alkylation of protected nucleosides in high yield is exemplified. [Copyright &y& Elsevier]

Published
2009
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