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Herein, we wish to report the scandium triflate catalyzed synthesis of novel dibenzo[ b,f ][1,5]oxazocin-6-ones in PEG-400 as a greener medium. Using this simple and greener protocol, for the very first time we have constructed novel eight-membered heterocyclic compounds in good yields. The PEG-Sc(OTf) 3 catalytic system can be reused for four consecutive runs without any significant loss of its catalytic activity. [ABSTRACT FROM AUTHOR]

In this communication, for the first time we have constructed a series of novel azo group fused 2 H -chromene-3-carboxylate and 3-acetyl-2 H -chromene derivatives via the Knoevenagel condensation reaction of active methylene compounds with aromatic 5-arylazosalicylaldehydes followed by a nucleophilic addition of the phenolic hydroxyl group to the carbonyl group of one of the ester groups. Shorter reaction times, high yields, simple work-up procedure and mild reaction conditions are the advantages of the present method. In addition, we have also studied the antioxidant activities using DPPH, hydroxyl, and ABTS radical scavenging methods. [ABSTRACT FROM AUTHOR]

A wide variety of nitriles react with sodium azide in the presence of a catalytic amount of cyanuric chloride or 2,4,6-trichloro-1,3,5-triazine (TCT) under mild reaction conditions to give the corresponding 5-substituted-1 H -tetrazoles in good to excellent yields. Here, we used TCT as a source of hydrochloric acid to catalyze this cycloaddition reaction. [ABSTRACT FROM AUTHOR]

In this Letter we wish to report a simple and efficient synthetic protocol for the synthesis of 5-substituted 1 H -tetrazole derivatives through the [2+3] cycloaddition of nitriles with sodium azide using ceric ammonium nitrate supported HY-zeolite as a novel catalyst. Excellent yields of the corresponding tetrazoles were obtained through this cost-effective protocol under aerobic conditions with shorter reaction time under mild reaction conditions. [ABSTRACT FROM AUTHOR]