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1. A novel linker for the attachment of alcohols to solid supports

Author

Rachael C. Hunter, Jean-Francois Pilard, James Dowden, David C. Rice, Benedicte Guilbert, Alison Haxton, Ian Burgess, Nicholas J. Turner, Sabine L. Flitsch, and Gerd Böhm

Subjects
chemistry.chemical_classification, Enzyme, chemistry, Organic Chemistry, Drug Discovery, food and beverages, Organic chemistry, Acid hydrolysis, Penicillin amidase, Biochemistry, Linker
Abstract

A novel linker for the immobilisation of alcohols on solid support is described. This linker can be cleaved either enzymatically using penicillin amidase, or by very mild acid hydrolysis using 10% TFA.

Published
1998
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