1. Systemic Effects of Intracoronary Nitroglycerin during Coronary Angiography in Children after Heart Transplantation
- Author
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Edward V. Colvin, Mary K. Olive, Robert N. Brown, Waldemar F. Carlo, Diego A. Lara, F. Bennett Pearce, James F. George, and Brad L. Steenwyck
- Subjects
Male ,medicine.medical_specialty ,Time Factors ,Adolescent ,Vasodilator Agents ,medicine.medical_treatment ,Coronary Vasospasm ,Blood Pressure ,Coronary Artery Disease ,Coronary Angiography ,Coronary artery disease ,Nitroglycerin ,Heart Rate ,Predictive Value of Tests ,Internal medicine ,Heart rate ,medicine ,Humans ,Clinical Investigation ,cardiovascular diseases ,Child ,Heart transplantation ,medicine.diagnostic_test ,business.industry ,Age Factors ,medicine.disease ,Blood pressure ,Child, Preschool ,Predictive value of tests ,Anesthesia ,Coronary vasospasm ,Angiography ,cardiovascular system ,Cardiology ,Heart Transplantation ,Female ,Cardiology and Cardiovascular Medicine ,business ,circulatory and respiratory physiology ,medicine.drug - Abstract
Coronary spasm during coronary angiography for vasculopathy in children can be prevented by the intracoronary administration of nitroglycerin. We reviewed the anesthesia and catheterization reports and charts for pediatric transplant recipients who underwent angiography from 2005 through 2010. Correlation analysis was used to study the relation of post-injection systolic blood pressure (SBP) to nitroglycerin dose. Forty-one angiographic evaluations were performed on 25 patients (13 male and 12 female). Mean age was 9.9 ± 3.2 years (range, 3.3–16.1 yr). The mean total dose of nitroglycerin was 2.93 ± 1.60 µg/kg (range, 1–8 µg/kg). There was a significant drop between the baseline SBP (mean, 106 ± 21.6 mmHg) and the lowest mean SBP before nitroglycerin administration (78 ± 13.2, P
- Published
- 2014
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