1. Bilateral acute retinal necrosis and herpes simplex type 2 encephalitis in a neonate
- Author
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Andres Kychenthal, John Greenwood, G W Aylward, Andrew Coombes, and Carlos Pavesio
- Subjects
Pathology ,medicine.medical_specialty ,Herpesvirus 2, Human ,Retinitis ,medicine.disease_cause ,Polymerase Chain Reaction ,Cellular and Molecular Neuroscience ,Lethargy ,Herpes virus ,medicine ,Humans ,Encephalitis, Viral ,Letters to the Editor ,Retinal necrosis ,Herpes Genitalis ,business.industry ,Infant, Newborn ,Retinal Necrosis Syndrome, Acute ,medicine.disease ,Sensory Systems ,Poor Feeding ,Ophthalmology ,Herpes simplex virus ,Immunology ,Acute retinal necrosis ,business ,Encephalitis - Abstract
Editor,—Acute retinal necrosis (ARN) is a rapidly progressing, sometimes devastating, retinitis associated with the herpes virus family. First described in 1971,1 it is diagnosed by the clinical triad of progressive peripheral retinal necrosis, occlusive vasculopathy, and vitreous inflammation.2 The association of herpetic encephalitis with ARN has been described in adults.34 Herpes simplex virus type 2 (HSV-2) has also been recognised as one of the causative agents of the ARN syndrome, particularly in Japan.5 It has been suggested that ARN in patients less than 25 years of age is likely to be caused by HSV-2.6 We present a case of bilateral ARN (BARN) in a neonate with HSV-2 encephalitis. ### CASE REPORT A 25 day old infant presented with a 4 day history of lethargy, poor feeding, and coughing. …
- Published
- 2001