1. Forced oscillation measurements in patients after lobectomy - A comparative analysis with IPF and COPD patients
- Author
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Dariusz Ziora, Sabina Kostorz-Nosal, and Dariusz Jastrzębski
- Subjects
Pulmonary and Respiratory Medicine ,Spirometry ,medicine.medical_specialty ,03 medical and health sciences ,Idiopathic pulmonary fibrosis ,FEV1/FVC ratio ,Pulmonary Disease, Chronic Obstructive ,0302 clinical medicine ,Forced Oscillation Technique ,Internal medicine ,Forced Expiratory Volume ,medicine ,Immunology and Allergy ,Plethysmograph ,Humans ,030212 general & internal medicine ,Lung cancer ,Lung ,Genetics (clinical) ,COPD ,medicine.diagnostic_test ,business.industry ,respiratory system ,medicine.disease ,Idiopathic Pulmonary Fibrosis ,respiratory tract diseases ,Respiratory Function Tests ,medicine.anatomical_structure ,030228 respiratory system ,Cardiology ,business - Abstract
OBJECTIVES Forced oscillation technique (FOT) is becoming increasingly widespread measurement method used for assessment of lung function. In the present study, we attempted to assess FOT values in patients after lobectomy in comparison with IPF and COPD patients. METHODS Twenty-two patients after lobectomy due to lung cancer stage I or II, 28 patients with idiopathic pulmonary fibrosis and 17 patients with chronic obstructive pulmonary disease were enrolled in the study. All patients performed spirometry (FEV1 , FVC, FEV1 /FVC, MEF50 , MEF25 , FEF25-75 , MIF50 ), plethysmography (Raw , TLC, RV, RV/TLC) and a test using the forced oscillation technique- resistance (R at 5Hz, 11Hz and 19Hz, inspiratory, expiratory and total), reactance (Xat 5Hz, 11Hz, inspiratory, expiratory and total), Fres and expiratory flow limitation (∆X). The ANOVA Kruskal-Wallis test followed by a multiple comparison test were used to evaluate the differences in oscillatory parameters between-groups. RESULTS Patients after lobectomy presented reduced X5, X11 and moderately increased R5, R11, R19, R5-19, ∆X and Fres. Rinsp 5 weresignificantly higher when compared with IPF patients (P = 0.001). In lobectomy patients R5, X5, X11, ∆X and Fres were significantly less affected when compared with patients with COPD (P
- Published
- 2020