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1. Mitochondrial Impairment Upregulates MICOS Expression in a Human Microglial Cell Model

Author

Huajun Jin, Vellareddy Anantharam, Arthi Kanthasamy, Emir Malovic, Anumantha G. Kanthasamy, and Alejandra Bargues Carot

Subjects
Dopaminergic, Genetics, medicine, Microglial cell, Disease, Biology, medicine.disease_cause, Molecular Biology, Biochemistry, Pathological, Oxidative stress, Biotechnology, Cell biology
Abstract

Mitochondrial dysfunction and oxidative stress have been implicated as key pathological mechanisms underlying the dopaminergic neurodegenerative process of Parkinson’s disease. The mitochondrial co...

Published
2019
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