1. Right ventricular function declines after cardiac surgery in adult patients with congenital heart disease
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Mark J. Schuuring, Berto J. Bouma, Barbara J.M. Mulder, Mark G. Hazekamp, Pauline P. M. Bolmers, Dave R. Koolbergen, Wim K. Lagrand, Stefan De Hert, E. M. F. H. de Beaumont, Rianne H.A.C.M. de Bruin-Bon, Amsterdam Cardiovascular Sciences, Cardiology, Cardiothoracic Surgery, Amsterdam institute for Infection and Immunity, Intensive Care Medicine, Anesthesiology, and Other Research
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Adult ,Heart Defects, Congenital ,Male ,medicine.medical_specialty ,Time Factors ,Heart disease ,Ventricular Dysfunction, Right ,Doppler echocardiography ,Risk Assessment ,law.invention ,Young Adult ,Troponin T ,law ,Risk Factors ,Internal medicine ,Cardiopulmonary bypass ,Medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Cardiac Surgical Procedures ,Creatine Kinase ,Cardiac imaging ,Netherlands ,Congenital heart disease ,Academic Medical Centers ,Original Paper ,Tricuspid valve ,Chi-Square Distribution ,medicine.diagnostic_test ,business.industry ,Recovery of Function ,Cardiac surgery ,medicine.disease ,Intensive care unit ,Right ventricular function ,Echocardiography, Doppler ,medicine.anatomical_structure ,Treatment Outcome ,Echocardiography ,Radiology Nuclear Medicine and imaging ,Cardiology ,Linear Models ,Ventricular Function, Right ,Female ,business ,Cardiology and Cardiovascular Medicine ,Biomarkers - Abstract
Right ventricular function (RVF) is often selectively declined after coronary artery bypass graft surgery. In adult patients with congenital heart disease (CHD) the incidence and persistence of declined RVF after cardiac surgery is unknown. The current study aimed to describe RVF after cardiac surgery in these patients. Adult CHD patients operated between January 2008 and December 2009 in the Academic Medical Centre in Amsterdam were studied. Clinical characteristics, laboratory tests, surgical data and intensive care unit outcome were obtained from medical records. RVF was measured by trans-thoracic echocardiography (TTE) and expressed by tricuspid annular plane systolic excursion (TAPSE), tissue Doppler imaging (RV S') and myocardial performance index (MPI) pre-operatively and direct, at intermediate and late follow up. Of a total of 185 operated, 86 patients (mean age 39 +/- A 13 years, 54% male) had echo data available. There was a significant fall in RVF after cardiac surgery. TAPSE and RV S' were significantly higher and MPI was significantly lower pre-operatively compared to direct post-operative values (TAPSE 22 +/- A 5 versus 13 +/- A 3 mm (P
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