1. The association of bariatric surgery and Dupuytren's disease: a propensity score-matched cohort study
- Author
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Dominic Furniss, Anders Thorell, Jennifer C E Lane, Andrea M. Burden, Theresa Burkard, and Dag Holmberg
- Subjects
Adult ,medicine.medical_specialty ,Bariatric Surgery ,body mass index ,Disease ,Cohort Studies ,Weight loss ,cohort study ,Medicine ,Humans ,Obesity ,Propensity Score ,Aged ,business.industry ,Hazard ratio ,Dupuytren's disease ,bariatric surgery ,obesity ,Middle Aged ,medicine.disease ,Confidence interval ,Surgery ,Dupuytren Contracture ,Propensity score matching ,Female ,medicine.symptom ,business ,Body mass index ,Cohort study - Abstract
We aimed to assess the association between bariatric surgery and incident Dupuytren's disease (DD) using propensity score-matched cohort studies among Swedish nationwide healthcare registries. Patients aged 30-79 years who underwent bariatric surgery 2006-2019 were matched on their propensity scores, up to two obese bariatric surgery-free (unexposed) patients. We applied Cox proportional hazard regression to calculate hazard ratios (HR) with 95% confidence intervals (CI) for the risk of DD overall, in subgroups of age, sex, bariatric surgery type and duration of follow-up. Among 34,959 bariatric surgery patients and 54,769 propensity score-matched obese patients, the risk of DD was increased in bariatric surgery patients compared with obese unexposed patients (HR 1.30, 95% CI 1.02-1.65), among women (HR 1.36; 1.00-1.84); those undergoing gastric bypass (HR 1.33; 1.04-1.71) and those with >5 years follow-up (HR 1.63; 1.14-2.34). Our results suggest that substantial weight loss is associated with an increased risk of DD in an obese population., Journal of Hand Surgery (European Volume), 47 (3), ISSN:1753-1934, ISSN:2043-6289
- Published
- 2021