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Your search keyword '"Koopmans, Marion P. G."' showing total 19 results
Start Over Author "Koopmans, Marion P. G." Journal the journal of infectious diseases
19 results on '"Koopmans, Marion P. G."'

4. Induction of Cross-Clade Antibody and T-Cell Responses by a Modified Vaccinia Virus Ankara–Based Influenza A(H5N1) Vaccine in a Randomized Phase 1/2a Clinical Trial

Author

de Vries, Rory D., Altenburg, Arwen F., Nieuwkoop, Nella J., de Bruin, Erwin, van Trierum, Stella E., Pronk, Mark R., Lamers, Mart M., Richard, Mathilde, Nieuwenhuijse, David F., Koopmans, Marion P. G., Kreijtz, Joost H. C. M., Fouchier, Ron A. M., Osterhaus, Albert D. M. E., Sutter, Gerd, and Rimmelzwaan, Guus F.

Published
2018

6. Ebola Virus Inactivation by Detergents Is Annulled in Serum

Author

van Kampen, Jeroen J. A., Tintu, Andrei, Russcher, Henk, Fraaij, Pieter L. A., Reusken, Chantal B. E. M., Rijken, Mikel, van Hellemond, Jaap J., van Genderen, Perry J. J., Koelewijn, Rob, de Jong, Menno D., Haddock, Elaine, Fischer, Robert J., Munster, Vincent J., and Koopmans, Marion P. G.

Published
2017

9. Clinical and In Vitro Evidence Favoring Immunoglobulin Treatment of a Chronic Norovirus Infection in a Patient With Common Variable Immunodeficiency

Author

van Kampen, Jeroen J A, primary, Dalm, Virgil A S H, additional, Fraaij, Pieter L A, additional, Oude Munnink, Bas B, additional, Schapendonk, Claudia M E, additional, Izquierdo-Lara, Ray W, additional, Villabruna, Nele, additional, Ettayebi, Khalil, additional, Estes, Mary K, additional, Koopmans, Marion P G, additional, and de Graaf, Miranda, additional

Published
2022
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11. Neutrophils Set Extracellular Traps to Injure Lungs in Coronavirus Disease 2019

Author

Ouwendijk, Werner J D, Raadsen, Matthijs P, van Kampen, Jeroen J A, Verdijk, Robert M, von der Thusen, Jan H, Guo, Lihui, Hoek, Rogier A S, van den Akker, Johannes P C, Endeman, Henrik, Langerak, Thomas, Molenkamp, Richard, Gommers, Diederik, Koopmans, Marion P G, van Gorp, Eric C M, Verjans, Georges M G M, and Haagmans, Bart L

Subjects
Male, 0301 basic medicine, Chemokine, ARDS, Computed Tomography Angiography, Neutrophils, Severity of Illness Index, Gastroenterology, Extracellular Traps, Cohort Studies, Pathogenesis, 0302 clinical medicine, Immunology and Allergy, Prospective Studies, 030212 general & internal medicine, Lung, Netherlands, Respiratory Distress Syndrome, biology, Middle Aged, Viral Load, Immunohistochemistry, Thrombosis, medicine.anatomical_structure, Editorial, AcademicSubjects/MED00290, Infectious Diseases, Female, Chemokines, medicine.symptom, Bronchoalveolar Lavage Fluid, Adult, medicine.medical_specialty, Critical Illness, neutrophil extracellular traps, Enzyme-Linked Immunosorbent Assay, 03 medical and health sciences, Internal medicine, Major Article, medicine, Humans, Aged, business.industry, SARS-CoV-2, COVID-19, Neutrophil extracellular traps, acute respiratory distress syndrome, medicine.disease, 030104 developmental biology, biology.protein, Sputum, business, Biomarkers, Respiratory tract
Abstract

Lower respiratory tract (LRT) disease induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can deteriorate to acute respiratory distress syndrome (ARDS). Because the release of neutrophil extracellular traps (NETs) is implicated in ARDS pathogenesis, we investigated the presence of NETs and correlates of pathogenesis in blood and LRT samples of critically ill patients with COVID-19. Plasma NET levels peaked early after intensive care unit admission and were correlated with the SARS-CoV-2 RNA load in sputum and levels of neutrophil-recruiting chemokines and inflammatory markers in plasma samples. The baseline plasma NET quantity was correlated with disease severity but was not associated with soluble markers of thrombosis or with development of thrombosis. High NET levels were present in LRT samples and persisted during the course of COVID-19, consistent with the detection of NETs in bronchi and alveolar spaces in lung tissue from deceased patient with COVID-19. Thus, NETs are produced and retained in the LRT of critically ill patients with COVID-19 and could contribute to SARS-CoV-2-induced ARDS disease.

Published
2021
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15. High Levels of Neutrophil Extracellular Traps Persist in the Lower Respiratory Tract of Critically Ill Patients With Coronavirus Disease 2019

Author

Ouwendijk, Werner J D, primary, Raadsen, Matthijs P, additional, van Kampen, Jeroen J A, additional, Verdijk, Robert M, additional, von der Thusen, Jan H, additional, Guo, Lihui, additional, Hoek, Rogier A S, additional, van den Akker, Johannes P C, additional, Endeman, Henrik, additional, Langerak, Thomas, additional, Molenkamp, Richard, additional, Gommers, Diederik, additional, Koopmans, Marion P G, additional, van Gorp, Eric C M, additional, Verjans, Georges M G M, additional, and Haagmans, Bart L, additional

Published
2021
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