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Start Over Author "Morse, Stephen" Journal the journal of infectious diseases
24 results on '"Morse, Stephen"'

5. Etiology of Genital Ulcers and Prevalence of Human Immunodeficiency Virus Coinfection in 10 US Cities

Author

Gential Ulcer Disease Surveillance Group, Mertz, Kristen J., Trees, David, Levine, William C., Lewis, Joel S., Litchfield, Billy, Pettus, Kevin S., Morse, Stephen A., St. Louis, Michael E., Weiss, Judith B., Schwebke, Jane, Dickes, James, Kee, Romina, Reynolds, James, Hutcheson, Don, Green, Donata, Dyer, Irene, Richwald, Gary A., Novotny, James, Weisfuse, Isaac, Goldberg, Martin, O'Donnell, Judith A., and Knaup, Richard

Published
1998

21. Transmission ofChlamydia trachomatisandNeisseria gonorrhoeaeamong Men with Urethritis and Their Female Sex Partners

Author

Lin, Juey‐Shin L., primary, Donegan, S. Patrick, additional, Heeren, Timothy C., additional, Greenberg, Marilyn, additional, Flaherty, Elizabeth E., additional, Haivanis, Ruth, additional, Su, Xiao‐Hong, additional, Dean, Deborah, additional, Newhall, Wilbert J., additional, Knapp, Joan S., additional, Sarafian, Samuel K., additional, Rice, Roselyn J., additional, Morse, Stephen A., additional, and Rice, Peter A., additional

Published
1998
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23. Comparison of Enzyme Immunoassays for Antibodies to Haemophilus ducreyi in a Community Outbreak of Chancroid in the United States

Author

Chen, Cheng-Yen, Mertz, Kristen J., Spinola, Stanley M., and Morse, Stephen A.

Abstract

The performance of two EIAs (adsorption EIA and lipooligosaccharide [LOS] EIA) that detect antibodies to Haemophilus ducreyi was evaluated with serum specimens obtained from 163 patients (96 with genital ulcer disease [GUD]). Paired serum specimens (initial and follow-up) were obtained from 52 of the GUD patients. By use of initial serum specimens from 82 GUD patients whose etiologic agents for their ulcers had been identified, the adsorption EIA had a sensitivity and specificity for chancroid of 53% and 71%, while the LOS EIA had a sensitivity and specificity of 48% and 89%, respectively. Sensitivity and specificity of the adsorption EIA increased to 78% and 84%, respectively, when the results of follow-up serum specimens were used to calculate optimal performance. The proportion of patients testing positive for H. ducreyi who had anti-H. ducreyi IgG antibodies, as determined by adsorption EIA, increased with the duration of infection, thus limiting the role of EIAs in the diagnosis of chancroid.

Published
1997
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24. Etiology of Genital Ulcers and Prevalence of Human Immunodeficiency Virus Coinfection in 10 US Cities

Author

Mertz, Kristen J., Trees, David, Levine, William C., Lewis, Joel S., Litchfield, Billy, Pettus, Kevin S., Morse, Stephen A., St. Louis, Michael E., Weiss, Judith B., Schwebke, Jane, Dickes, James, Kee, Romina, Reynolds, James, Hutcheson, Don, Green, Donata, Dyer, Irene, Richwald, Gary A., Novotny, James, Weisfuse, Isaac, Goldberg, Martin, O'Donnell, Judith A., Knaup, Richard, and Group, Genital Ulcer Disease Surveillance

Abstract

To determine the etiology of genital ulcers and to assess the prevalence of human immunodeficiency virus (HIV) infection in ulcer patients in 10 US cities, ulcer and serum specimens were collected from ∼50 ulcer patients at a sexually transmitted disease clinic in each city. Ulcer specimens were tested using a multiplex polymerase chain reaction assay to detect Haemophilus ducreyi, Treponema pallidum, and herpes simplex virus (HSV); sera were tested for antibody to HIV. H. ducreyi was detected in ulcer specimens from patients in Memphis (20% of specimens) and Chicago (12%). T. pallidum was detected in ulcer specimens from every city except Los Angeles (median, 9% of specimens; range, 0%–46%). HSV was detected in ≥50% of specimens from all cities except Memphis (42%). HIV seroprevalence in ulcer patients was 6% (range by city, 0%–18%). These data suggest that chancroid is prevalent in some US cities and that persons with genital ulcers should be a focus of HIV prevention activities.

Published
1998
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