1. A mediterranean diet is cost-effective in patients with previous myocardial infarction
- Author
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Leonie Segal, Kim Dalziel, Michel de Lorgeril, De Lorgeril, Michel, Techniques de l'Ingénierie Médicale et de la Complexité - Informatique, Mathématiques et Applications, Grenoble - UMR 5525 (TIMC-IMAG), and VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF)
- Subjects
Gerontology ,Heart disease ,Mediterranean diet ,Cost effectiveness ,Cost-Benefit Analysis ,Comparative effectiveness research ,Myocardial Infarction ,Medicine (miscellaneous) ,030204 cardiovascular system & hematology ,Diet, Mediterranean ,Coronary artery disease ,03 medical and health sciences ,0302 clinical medicine ,[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system ,MESH: Markov Chains ,medicine ,Humans ,030212 general & internal medicine ,health care economics and organizations ,2. Zero hunger ,MESH: Diet, Mediterranean ,Cost–utility analysis ,Nutrition and Dietetics ,MESH: Humans ,MESH: Middle Aged ,Cost–benefit analysis ,business.industry ,Middle Aged ,medicine.disease ,Markov Chains ,Quality-adjusted life year ,[SDV.MHEP.CSC] Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system ,MESH: Myocardial Infarction ,MESH: Quality-Adjusted Life Years ,Quality-Adjusted Life Years ,business ,Demography ,MESH: Cost-Benefit Analysis - Abstract
International audience; This evaluation aimed to assess the economic performance of the Mediterranean diet for patients after a first acute myocardial infarction (AMI). A cost utility analysis using a Markov model was used to compare the Mediterranean diet to a prudent Western diet over a time frame of 10 years. After a systematic review of the literature, program effectiveness was based on the Lyon Diet Heart Study (605 patients, mean age 54 y, randomized to the Mediterranean diet delivered by a dietician and cardiologist, or a prudent Western diet). Costs were estimated in AU$ [and converted to US$ and Euros (euro)] based on the resource use to which published unit costs were applied. Cost and benefits were discounted at 5% per annum. The main outcome measure was cost per quality-adjusted life year (QALY) gained. Extensive 1-way sensitivity analyses were performed. The Mediterranean diet compared with a prudent Western diet was estimated to cost AU$1013 (US$703, euro579) per QALY gained per person. There was a mean gain in life years of 0.31/person and a gain in quality-adjusted life years of 0.40/person. Based on the published results from the Lyon Diet Heart Study and conservative assumptions, the Mediterranean diet is highly cost-effective for persons after a first AMI and represents an exceptional return on investment. Policy makers should strongly consider the generalizability of results to their own setting.
- Published
- 2006