1. Respiratory health in prematurely born preschool children with and without bronchopulmonary dysplasia
- Author
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H.M. Boezen, Eric J. Duiverman, Jorrit Gerritsen, Elianne J.L.E. Vrijlandt, E.F. Stremmelaar, Faculteit Medische Wetenschappen/UMCG, Life Course Epidemiology (LCE), and Groningen Research Institute for Asthma and COPD (GRIAC)
- Subjects
Male ,Pediatrics ,medicine.medical_specialty ,PRETERM BIRTH ,Birth weight ,Developmental Disabilities ,Respiratory physiology ,behavioral disciplines and activities ,Statistics, Nonparametric ,Pulmonary function testing ,Cohort Studies ,Sex Factors ,FLOW LIMITATION ,Reference Values ,mental disorders ,Prevalence ,Medicine ,Birth Weight ,Humans ,BRONCHODILATOR RESPONSE ,Respiratory system ,Bronchopulmonary Dysplasia ,FORCED OSCILLATION TECHNIQUE ,business.industry ,Respiratory disease ,SCHOOL-AGE ,Age Factors ,Infant, Newborn ,Oxygen Inhalation Therapy ,PULMONARY-FUNCTION ,Gestational age ,HYALINE-MEMBRANE DISEASE ,medicine.disease ,Prognosis ,Respiratory Function Tests ,Bronchopulmonary dysplasia ,CHRONIC LUNG-DISEASE ,Case-Control Studies ,Child, Preschool ,Pediatrics, Perinatology and Child Health ,ASTHMATIC-CHILDREN ,Respiratory Mechanics ,Respiratory Physiological Phenomena ,Female ,business ,Infant, Premature ,Cohort study ,Follow-Up Studies - Abstract
Objective: To investigate the respiratory health of preterm infants with bronchopulmonary dysplasia (BPD) at preschool age and to determine whether lung function (measured by forced oscillation technique (FOT) and interruption technique (Rint) is affected by BPD in preterm infants compared with preterm infants without BPD.Study design: Participants: 3 to 5 years of age born preterm with BPD (N = 40, mean gestational age 28 weeks, mean birth weight 1051 g), and without BPD (N = 36, mean gestational age 29 weeks, mean birth weight 1179 g). Outcome variables: prevalence of symptoms determined by European Community Respiratory Health Survey and lung function measured by FOT and Rint.Results: A large percentage of infants in both preterm groups reported respiratory symptoms during the last 12 months. Lung function measurements showed higher resonant frequency (Hz) in BPD compared with non-BPD (mean 26.8 vs 22.7, P Conclusion: Preterm birth affects respiratory health at 3 to 5 years of age. Children with BPD could be distinguished from children without BPD based on a higher resonant frequency and a lower mean reactance.
- Published
- 2006