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Start Over Author "Naya A" Journal the journal of urology
48 results on '"Naya A"'

5. THE COMPARISON ONE IMMEDIATE POSTOPERATIVE INTRAVESICAL CHEMOTHERAPY WITH SHORT-TERM ADJUVANT INTRAVESICAL CHEMOTHERAPY AFTER TURBT IN LOW- AND INTERMEDIATE RECURRENT RISK OF NON-MUSCLE-INVASIVE BLADDER CANCER- A RANDOMIZED PROSPECTIVE STUDY IN JAPAN.: MP13-08

Author

Naya, Yoshio, Shiraishi, Takumi, Oishi, Masakatsu, Ueda, Takashi, Nakanshi, Hiroyuki, Naitoh, Yasuyuki, Nakamura, Terukazu, Hongo, Fumiya, Kamoi, Kazumi, Okihara, Koji, Mikami, Kazuya, Iwata, Tsuyoshi, and Ukimura, Osamu

Published
2016
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21. COMPARATIVE MORPHOMETRIC STUDY OF BLADDER DETRUSOR BETWEEN PATIENTS WITH BENIGN PROSTATIC HYPERPLASIA AND CONTROLS

Author

Emi Inui, Munekado Kojima, A. Ochiai, Yoshio Naya, and Osamu Ukimura

Subjects
Male, Detrusor muscle, medicine.medical_specialty, Pathology, medicine.medical_treatment, Urology, Urinary Bladder, Prostatic Hyperplasia, Connective tissue, urologic and male genital diseases, Muscle hypertrophy, Masson's trichrome stain, Prostate, medicine, Humans, Aged, Aged, 80 and over, Urinary bladder, business.industry, Prostatectomy, Muscle, Smooth, Hypertrophy, Middle Aged, Hyperplasia, medicine.disease, medicine.anatomical_structure, Connective Tissue, Female, business
Abstract

We determined the change in the amount of connective tissue of the detrusor in patients with benign prostatic hyperplasia (BPH) in relation to the degree of bladder hypertrophy by ultrasound estimated bladder weight. The ratio of connective tissue-to-smooth muscle between controls and BPH cases was compared.For normal controls we used cadaver bladders excised at autopsy from 13 men with no urinary tract diseases. Bladder wall samples were also obtained at subcapsular prostatectomy for BPH in 26 patients. On thin sections stained with Masson trichrome, the ratio of connective tissue-to-smooth muscle was measured using a computer assisted color image analysis. This ratio was compared in BPH cases with estimated bladder weight, which was measured preoperatively using transabdominal ultrasonography.A connective tissue-to-smooth muscle ratio ranged from 19.8 to 28.2% (mean plus or minus standard deviation 24.7+/-2.4) and from 12.9 to 53.3% (27.3+/-9.9) in control and BPH cases, respectively. In BPH cases a significant correlation was noted between estimated bladder weight and connective tissue-to-smooth muscle ratio (r=0.788, p0.0001). Interestingly, in BPH cases with an estimated bladder weight of less than 60 gm. the ratio ranged from 12.9 to 30.4% (22.8+/-4.9), which was not significantly different compared to control cases. In contrast, in all BPH cases with an estimated bladder weight of 60 gm. or more connective tissue-to-smooth muscle ratio increased significantly to more than 30% (range 33.4 to 53.3%, mean 42.2+/-13.6%).These results suggest that abnormal increase of connective tissue in addition to smooth muscle hypertrophy and/or hyperplasia could contribute to advanced bladder hypertrophy caused by infravesical obstruction.

Published
1999
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23. The predictors of pelvic lymph node metastasis at radical retropubic prostatectomy

Author

Yoshio Naya and R. Joseph Babaian

Subjects
Adult, Male, medicine.medical_specialty, Urology, medicine.medical_treatment, Metastasis, Pelvis, Risk Factors, Biopsy, medicine, Humans, Stage (cooking), Lymph node, Aged, Prostatectomy, medicine.diagnostic_test, business.industry, Patient Selection, Biopsy, Needle, Prostatic Neoplasms, Middle Aged, Prostate-Specific Antigen, medicine.disease, Prognosis, Surgery, Prostate-specific antigen, Dissection, medicine.anatomical_structure, Logistic Models, Lymphatic Metastasis, business, Algorithms, Radical retropubic prostatectomy
Abstract

We studied preoperative variables in a contemporary series of patients who underwent radical retropubic prostatectomy (RRP) to determine which variables were associated with lymph node metastasis.Between January 1995 and November 1999, 1,091 men underwent RRP, 695 of whom underwent bilateral pelvic lymph node dissection without any prior therapy. We evaluated biopsy Gleason score, maximum tumor length and maximum percentage of tumor in the positive core(s), location and number of positive cores, and total prostate specific antigen before surgery in 295 of these patients. We also developed a classification and regression tree analysis algorithm to segregate the risk of positive lymph node metastasis. Stepwise logistic regression analyses were used to determine independent predictors of lymph node metastasis.Of the 695 patients 19 (2.7%) had lymph node metastasis. Clinical stage, Gleason score, positive basal core, greatest percentage of tumor on positive cores and maximum tumor length in positive core were significant predictors of lymph node metastasis in the Mann-Whitney U test and chi-square test. Classification and regression trees analysis revealed that 4 or more positive cores with any Gleason grade 4 or 5, serum prostate specific antigen 15.0 ng/ml or greater, or the presence of dominant Gleason 4 or 5 were independent predictors of lymph node metastasis. Our algorithm had a significantly higher diagnostic performance than the Hamburg algorithm (p = 0.002).Our algorithm may be a valid tool for the prediction of lymph node metastasis and may help to select men who do not need to undergo bilateral pelvic lymph node dissection with RRP.

Published
2003

24. Noninvasive evaluation of bladder compliance in children using ultrasound estimated bladder weight

Author

Yoshio Naya, Emi Inui, Hiroki Watanabe, Akihiro Kawauchi, Osamu Ukimura, Munekado Kojima, and Atsushi Ochiai

Subjects
Adult, Male, medicine.medical_specialty, Adolescent, Bladder compliance, Estimated Weight, Urinary system, Urology, Urinary Bladder, Patient age, Reference Values, medicine, Humans, Child, Ultrasonography, Urinary bladder, business.industry, Ultrasound, Urinary Bladder Diseases, Mean age, Organ Size, Surgery, Urodynamics, medicine.anatomical_structure, Child, Preschool, Female, Linear correlation, business, Nuclear medicine, Compliance
Abstract

In healthy children as well as those with urinary disturbance we determined ultrasound estimated bladder weight with the aim of revealing its possible usefulness as a measure of bladder compliance.We measured ultrasound estimated bladder weight in 71 healthy children with a mean age of 10.3 years, and determined a standard value. A total of 82 patients with a mean age of 9.6 years with urinary disturbance also underwent ultrasound estimated bladder weight measurement as well as conventional urological examinations, including filling cystometry.In healthy children ultrasound estimated bladder weight increased with age, showing a significant linear correlation (r = 0.80, p0.0001). Using the formula for linear correlation, 0.86 x patient age + 6.9 gm., we obtained an age matched estimated weight. In 82 patients the percent deviation of the estimate from age matched values was calculated using the formula, (measured ultrasound estimated bladder weight -age matched ultrasound estimated bladder weight)/age matched ultrasound estimated bladder weight x 100, and then correlated with bladder compliance. In 75 of 77 patients (97%) with compliance of 10 ml./cm. water or more the estimate was within 100% deviation. In contrast, 4 of 5 patients (80%) with a low compliant bladder (less than 10 ml./cm. water) had an ultrasound estimated bladder weight greater than 100% deviation. When the estimate was within 100% deviation, all but 1 patient (75 of 76, 98.7%) had compliance of 10 ml./cm. water or more compared to 33.3% (2 of 6) of those with an estimate greater than 100% deviation. As a result, with the use of a cutoff value of 100% deviation ultrasound estimated bladder weight predicted a low compliant bladder with a diagnostic accuracy as high as 96.3% (79 of 82 cases).Ultrasound estimated bladder weight may be used to evaluate bladder compliance in children. It seems to be a suitable noninvasive urodynamic test in children with suspected urodynamic abnormalities.

Published
1998

25. Noninvasive quantitative estimation of infravesical obstruction using ultrasonic measurement of bladder weight

Author

Osamu Ukimura, Hiroki Watanabe, Munekado Kojima, Atsushi Ochiai, Yoshio Naya, and Emi Inui

Subjects
Male, medicine.medical_specialty, Urethral resistance, Urology, Urinary system, Urinary Bladder, Prostatic Hyperplasia, urologic and male genital diseases, Predictive Value of Tests, Medicine, Humans, False Positive Reactions, False Negative Reactions, Aged, Ultrasonography, Aged, 80 and over, Urinary symptoms, business.industry, Specific weight, Ultrasound, Organ Size, Middle Aged, female genital diseases and pregnancy complications, Surgery, Urinary Bladder Neck Obstruction, Urethra, medicine.anatomical_structure, Predictive value of tests, Ultrasonic sensor, business, Nuclear medicine
Abstract

Purpose: Ultrasound estimated bladder weight was compared to pressure-flow studies to test the ability of ultrasound estimated bladder weight to predict infravesical obstruction.Materials and Methods: A total of 65 men with urinary symptoms underwent ultrasonic measurement of bladder weight and pressure-flow studies. Assuming the bladder is a sphere, ultrasound estimated bladder weight was calculated from bladder wall thickness measured ultrasonically and intravesical volume.Results: Ultrasound estimated bladder weight correlated significantly (p

Published
1997

46. 1125: Identification of A Novel Missense Mutation of SLC7A9 Frequent in Japanese Cystinuria Population that Cause Membrane Targeting Defect of the Transporter Protein by Introducing A Bulky Side Chain on its C -Terminus

Author

Sakamoto, Shinichi, Shigeta, Yasuhiro, Ueda, Takeshi, Chairoungdua, Arthit, Fujimura, Masanori, Awa, Yusuke, Naya, Yukio, Akakura, Koichiro, Ichikawa, Tomohiko, Igarashi, Tatsuo, Kanai, Yoshikatsu, Endou, Hitoshi, and Ito, Haruo

Published
2004
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48. Seminal Vesicle Parameters at 10-Year Intervals Measured by Transrectal Ultrasonography

Author

Terasaki, Toyohiro, Watanabe, Hiroki, Kamoi, Kazumi, and Naya, Yoshio

Abstract

The volume, maximum horizontal area, maximum length, maximum width and depth of the seminal vesicles were measured by transrectal ultrasonography in 76 subjects without seminal vesicle disorders, divided into 7 groups at 10-year intervals. The average of each parameter in each group was presented. The volume and maximum horizontal area began to decrease after the age of 60 years. No statistically significant difference among subject ages was observed for the other 3 parameters. A correlation was observed between the volume and maximum horizontal area of the seminal vesicles. Our study confirmed that maximum horizontal area of the seminal vesicles may be substituted for the volume.

Published
1993
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