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6. Intracranial pressure in African children with cerebral malaria

Author

Newton, C.R.J.C., Kirkham, F.J., Winstanley, P.A., Pasvol, G., Peshu, N., Warrell, D.A., and Marsh, K.

Subjects
Malaria -- Care and treatment, Malaria -- Complications, Malaria -- Kenya, Intracranial hypertension -- Development and progression, Intracranial pressure -- Measurement
Published
1991

7. Averting a malaria disaster

Author

White, N J, Nosten, F, Looareesuwan, S, Watkins, W M, Marsh, K, Snow, R W, Kokwaro, G, Ouma, J, Hien, T T, Molyneux, M E, Taylor, T E, Newbold, C I, Ruebush, T K, Danis, M, Greenwood, B M, Anderson, R M, and Olliaro, P

Published
1999

9. Diagnosis of bacterial meningitis

Author

Obaro, S K, Enwere, G E, Newton, C R J C, Marsh, K, Mwangi, I, Lowe, B, and Berkley, J

Subjects
Meningitis -- Diagnosis, Cerebrospinal fluid -- Analysis
Published
2001

10. A non-sense mutation and protection from severe malaria

Author

Konotey-Ahulu, Felix I D, Roberts, D J, Marsh, K, Oscar, K, Pain, A, Taylor, Terrie, Molyneux, Malcolm, and Rogerson, Stephen

Subjects
Malaria -- Risk factors, Gene mutations -- Health aspects
Published
2001

11. Phenobarbital for children with cerebral malaria

Author

Verhoef, Hans, West, Clive E, Kok, Frans J, Crawley, Jane, Waruiru, C, Winstanley, P, Peto, T, and Marsh, K

Subjects
Malaria, Seizures (Medicine), Phenobarbital -- Health aspects
Published
2000

16. Cerebral malaria

Author

Hall, AnthonyP, primary, Kwiatkowski, Dominic, additional, Molyneux, Malcolm, additional, Taylor, Terrie, additional, Klein, Nigel, additional, Curtis, Nigel, additional, Smit, Margot, additional, Greenwood, B.M, additional, Poser, CharlesM, additional, Roman, GustavoC, additional, Kirkham, F.J, additional, Newton, C.R.J.C, additional, Winstanley, P.A, additional, Pasvol, G, additional, Peshu, N, additional, Warrell, D.A, additional, Marsh, K, additional, Birley, HumphreyD.L, additional, Mabey, DavidC.W, additional, and Singer, Mervyn, additional

Published
1991
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17. HYPOGLYCAEMIA IN AFRICAN CHILDREN WITH SEVERE MALARIA

Author

White, N.J., Marsh, K., Turner, R.C., Miller, K.D., Berry, C.D., Williamson, D.H., and Brown, J.

Abstract

Hypoglycaemia, defined as a plasma glucose concentration below 2·2 mmol/l, developed in 15 of 47 prospectively studied Gambian children with severe chloroquine-sensitive falciparum malaria. 5 of these hypoglycaemic children died compared with 1 in the normoglycaemic group (p = 0·02). In contrast to previous observations in quinine-treated adults, in whom hypoglycaemia was associated with hyperinsulinaemia, plasma concentrations of insulin were appropriately low and plasma ketones were high. Raised plasma concentrations of lactate and alanine suggested impairment of hepatic gluconeogenesis. In African children, hypoglycaemia is an important and treatable manifestation of severe malaria and is unrelated to antimalarial treatment.

Published
1987
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