1. Laboratory capacity assessments in 25 African countries at high risk of yellow fever, August-December 2018
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Barbara Wilmot Johnson, Maurice Demanou, Gamou Fall, Jean-Luc Betoulle, Celestina Obiekea, Alison Jane Basile, Cristina Domingo, Christin Goodman, Eric Mossel, Chantal Reusken, Erin Staples, Joana Filipa Machado de Morais, Zoraima Neto, Paula Paixão, Yves Eric Denon, Mariette Glitho, José Mahinou, Therese Kagone, Emmanuel Nakoune, Kadidja Gamougam, Elisabeth Pukuta Simbu, Steve Ahuka, Jean-Vivien Mombouli, Cynthia Goma-Nkoua, Edgard Valery Adjogoua, Adamu Tayachew, Berhane Beyene, Bakary Sanneh, Modou Lamin Jarju, Alphonse Mendy, Dodzi Kofi Amelor, Lawrence Ofosu-Appiah, David Opare, Lorreta Antwi, Rexford Adade, N'Faly Magassouba, Sabado Fernandes Gomes, Samson Limbaso, Joel Lutomiah, Burgess Gbelee Jr, John Dogba, Issa Cisse, Zakou Idde, Chikwe Ihekweazu, Nwando Mba, Ousmane Faye, Oumar Faye, Amadou Alpha Sall, Zikan Koroma, Manuela Alphonse Juma, James Ayei Maror, Mawahib Eldigail, Adel Hussein Elduma, Rehab Elageb, Kossi Badziklou, Koba Adjaho Komla, John Kayiwa, Julius Julian Lutwama, Lee Hampton, and Mick Norman Mulders
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yellow fever ,laboratory ,diagnostics ,testing ,Medicine - Abstract
INTRODUCTION: accurate and timely laboratory diagnosis of yellow fever (YF) is critical to the Eliminate Yellow Fever Epidemics (EYE) strategy. Gavi, the Vaccine Alliance recognized the need to support and build capacity in the national and regional laboratories in the Global YF Laboratory Network (GYFLN) as part of this strategy. METHODS: to better understand current capacity, gaps and needs of the GYFLN laboratories in Africa, assessments were carried out in national and regional reference laboratories in the 25 African countries at high risk for YF outbreaks that were eligible for new financial support from Gavi. RESULTS: the assessments found that the GYFLN in Africa has high capacity but 21% of specimens were not tested due to lack of testing kits or reagents and approximately 50% of presumptive YF cases were not confirmed at the regional reference laboratory due to problems with shipping. CONCLUSION: the laboratory assessments helped to document the baseline capacities of these laboratories prior to Gavi funding to support strengthening YF laboratories.
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- 2021
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