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Start Over Author "Modi, G." Journal thrombosis research
4 results on '"Modi, G."'

4. The isolation of prothrombin, Factor IX and Factor X from human Factor IX concentrates.

Author

Modi GJ, Blajchman MA, and Ofosu FA

Subjects
Chromatography, Agarose, Chromatography, Ion Exchange, Dextran Sulfate, Dextrans, Humans, Sepharose analogs & derivatives, Factor IX isolation & purification, Factor X isolation & purification, Prothrombin isolation & purification
Abstract

A relatively simple and reproducible procedure is described for the isolation of functionally and electrophoretically homogeneous prothrombin, factor IX and factor X from clinical Factor IX Concentrates. The procedure involves ammonium sulphate fractionation; then chromatography on DEAE-Sephadex A50, dextran sulphate-Sepharose and heparin-Sepharose. High recovery of all three procoagulants was obtained: 32% for factor IX; 32% for factor X; 29% for prothrombin.

Published
1984
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