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1. Standardized Map of Iodine Status in Europe

Author

Ittermann, Till, primary, Albrecht, Diana, additional, Arohonka, Petra, additional, Bilek, Radovan, additional, de Castro, Joao J., additional, Dahl, Lisbeth, additional, Filipsson Nystrom, Helena, additional, Gaberscek, Simona, additional, Garcia-Fuentes, Eduardo, additional, Gheorghiu, Monica L., additional, Hubalewska-Dydejczyk, Alicja, additional, Hunziker, Sandra, additional, Jukic, Tomislav, additional, Karanfilski, Borislav, additional, Koskinen, Seppo, additional, Kusic, Zvonko, additional, Majstorov, Venjamin, additional, Makris, Konstantinos C., additional, Markou, Kostas B., additional, Meisinger, Christa, additional, Milevska Kostova, Neda, additional, Mullen, Karen R., additional, Nagy, Endre V., additional, Pirags, Valdis, additional, Rojo-Martinez, Gemma, additional, Samardzic, Mira, additional, Saranac, Ljiljana, additional, Strele, Ieva, additional, Thamm, Michael, additional, Top, Işık, additional, Trofimiuk-Müldner, Malgorzata, additional, Ünal, Belgin, additional, Valsta, Liisa, additional, Vila, Lluis, additional, Vitti, Paolo, additional, Winter, Benjamin, additional, Woodside, Jayne V., additional, Zaletel, Katja, additional, Zamrazil, Vaclav, additional, Zimmermann, Michael, additional, Erlund, Iris, additional, and Völzke, Henry, additional

Published
2020
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2. Patients with Indeterminate Thyroid Nodules at Cytology and Cancer at Histology Have a More Favorable Outcome Compared with Patients with Suspicious or Malignant Cytology

Author

Rago, Teresa, primary, Scutari, Maria, additional, Loiacono, Valeria, additional, Tonacchera, Massimo, additional, Scuotri, Giuditta, additional, Romani, Rossana, additional, Proietti, Agnese, additional, Piaggi, Paolo, additional, Elisei, Rossella, additional, Basolo, Fulvio, additional, Latrofa, Francesco, additional, and Vitti, Paolo, additional

Published
2018
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3. Changing Trend of Thyroglobulin Antibodies in Patients With Differentiated Thyroid Cancer Treated With Total Thyroidectomy Without131I Ablation

Author

Matrone, Antonio, primary, Latrofa, Francesco, additional, Torregrossa, Liborio, additional, Piaggi, Paolo, additional, Gambale, Carla, additional, Faranda, Alessio, additional, Ricci, Debora, additional, Agate, Laura, additional, Molinaro, Eleonora, additional, Basolo, Fulvio, additional, Vitti, Paolo, additional, and Elisei, Rossella, additional

Published
2018
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5. High Serum Cholesterol Is a Novel Risk Factor for Graves' Orbitopathy: Results of a Cross-Sectional Study

Author

Sabini, Elena, primary, Mazzi, Barbara, additional, Profilo, Maria Antonietta, additional, Mautone, Teresa, additional, Casini, Giamberto, additional, Rocchi, Roberto, additional, Ionni, Ilaria, additional, Menconi, Francesca, additional, Leo, Marenza, additional, Nardi, Marco, additional, Vitti, Paolo, additional, Marcocci, Claudio, additional, and Marinò, Michele, additional

Published
2018
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9. Low Elasticity of Thyroid Nodules on Ultrasound Elastography Is Correlated with Malignancy, Degree of Fibrosis, and High Expression of Galectin-3 and Fibronectin-1

Author

Rago, Teresa, primary, Scutari, Maria, additional, Loiacono, Valeria, additional, Santini, Ferruccio, additional, Tonacchera, Massimo, additional, Torregrossa, Liborio, additional, Giannini, Riccardo, additional, Borrelli, Nicla, additional, Proietti, Agnese, additional, Basolo, Fulvio, additional, Miccoli, Paolo, additional, Piaggi, Paolo, additional, Latrofa, Francesco, additional, and Vitti, Paolo, additional

Published
2017
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11. Weight Loss and Variation of Levothyroxine Requirements in Hypothyroid Obese Patients After Bariatric Surgery

Author

Fierabracci, Paola, primary, Martinelli, Silvia, additional, Tamberi, Anna, additional, Piaggi, Paolo, additional, Basolo, Alessio, additional, Pelosini, Caterina, additional, Ricco, Ilaria, additional, Magno, Silvia, additional, Querci, Giorgia, additional, Ceccarini, Giovanni, additional, Scartabelli, Giovanna, additional, Salvetti, Guido, additional, Vitti, Paolo, additional, and Santini, Ferruccio, additional

Published
2016
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12. Changing Trend of Thyroglobulin Antibodies in Patients With Differentiated Thyroid Cancer Treated With Total Thyroidectomy Without 131I Ablation.

Author

Matrone, Antonio, Latrofa, Francesco, Gambale, Carla, Faranda, Alessio, Ricci, Debora, Agate, Laura, Molinaro, Eleonora, Vitti, Paolo, Elisei, Rossella, Torregrossa, Liborio, Basolo, Fulvio, and Piaggi, Paolo

Subjects
THYROGLOBULIN, THYROID cancer treatment, IMMUNOGLOBULINS, THYROIDECTOMY, IODINE isotopes, ABLATION techniques
Abstract

Background: Thyroglobulin (Tg) antibodies (TgAb) can interfere with Tg measurement and can be used as “Tg surrogate” in patients with differentiated thyroid cancer (DTC) treated with total thyroidectomy (TTx) and radioiodine remnant ablation (RRA). In contrast, few data, and in patients usually followed for a short-term follow-up, have been reported about the changes of TgAb levels in patients treated with TTx but without RRA. The aims of this study were to evaluate the changes of TgAb levels in DTC patients treated with TTx but not RRA and to identify the factors that influence these changes. Methods: The change in TgAb levels in 107 DTC (<1 cm) patients submitted to TTx but not RRA was evaluated. Patients were followed for a median of 6.3 years, and all had at least three determinations of TgAb and neck ultrasound (nUS). Results: TgAb levels showed a progressive decrease during follow-up. Initial TgAb levels and degree of lymphocytic infiltration influenced the time but not the rate of TgAb disappearance. No influence on time and rate of the decrease in TgAb was observed when the association with thyroperoxidase antibodies (TPOAb) levels were considered. A TgAb cutoff value of 61.9 IU/mL at first postoperative evaluation was a good indicator for disappearance of the TgAb within six years. No tumor recurrence was observed in the series. In one case, the progressive increase in TgAb anticipated the reappearance of benign thyroid tissue with lymphocytic infiltration. Conclusions: TgAb levels decline in the majority of DTC patients treated with TTx but not ablated with radioiodine. The levels decrease rapidly after the surgical treatment and continue to decrease over time. The time of disappearance is influenced by the initial TgAb levels and the degree of lymphocytic infiltration. No influence of the actual TPOAb levels has been observed. An increase in TgAb levels should not be overlooked, since it can indicate the presence or reappearance of either normal thyroid tissue or tumor recurrence. [ABSTRACT FROM AUTHOR]

Published
2018
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13. Age and Dose Are Major Risk Factors for Liver Damage Associated with Intravenous Glucocorticoid Pulse Therapy for Graves' Orbitopathy

Author

Sisti, Eleonora, primary, Coco, Barbara, additional, Menconi, Francesca, additional, Leo, Marenza, additional, Rocchi, Roberto, additional, Latrofa, Francesco, additional, Profilo, Maria Antonietta, additional, Mazzi, Barbara, additional, Vitti, Paolo, additional, Marcocci, Claudio, additional, Brunetto, Maurizia, additional, and Marinò, Michele, additional

Published
2015
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14. Role of the Underlying Thyroid Disease on the Phenotype of Graves' Orbitopathy in a Tertiary Referral Center

Author

Leo, Marenza, primary, Menconi, Francesca, additional, Rocchi, Roberto, additional, Latrofa, Francesco, additional, Sisti, Eleonora, additional, Profilo, Maria Antonietta, additional, Mazzi, Barbara, additional, Albano, Eleonora, additional, Nardi, Marco, additional, Vitti, Paolo, additional, Marcocci, Claudio, additional, and Marinò, Michele, additional

Published
2015
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15. FoxP3 Expression in Papillary Thyroid Carcinoma: A Possible Resistance Biomarker to Iodine 131 Treatment

Author

Ugolini, Clara, primary, Elisei, Rossella, additional, Proietti, Agnese, additional, Pelliccioni, Serena, additional, Lupi, Cristiana, additional, Borrelli, Nicla, additional, Viola, David, additional, Leocata, Pietro, additional, Vitti, Paolo, additional, Miccoli, Paolo, additional, Toniolo, Antonio, additional, and Basolo, Fulvio, additional

Published
2014
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17. Thyroid Volume and Severity of Graves' Orbitopathy

Author

Profilo, Maria Antonietta, primary, Sisti, Eleonora, additional, Marcocci, Claudio, additional, Vitti, Paolo, additional, Pinchera, Aldo, additional, Nardi, Marco, additional, Rocchi, Roberto, additional, Latrofa, Francesco, additional, Menconi, Francesca, additional, Altea, Maria Antonietta, additional, Leo, Marenza, additional, Rago, Teresa, additional, and Marinò, Michele, additional

Published
2013
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18. Enalapril Reduces Proliferation and Hyaluronic Acid Release in Orbital Fibroblasts

Author

Botta, Roberta, primary, Lisi, Simonetta, additional, Marcocci, Claudio, additional, Sellari-Franceschini, Stefano, additional, Rocchi, Roberto, additional, Latrofa, Francesco, additional, Menconi, Francesca, additional, Altea, Maria Antonietta, additional, Leo, Marenza, additional, Sisti, Eleonora, additional, Casini, Giamberto, additional, Nardi, Marco, additional, Pinchera, Aldo, additional, Vitti, Paolo, additional, and Marinò, Michele, additional

Published
2013
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19. Rehabilitative Orbital Decompression for Graves' Orbitopathy: Risk Factors Influencing the New Onset of Diplopia in Primary Gaze, Outcome, and Patients' Satisfaction

Author

Rocchi, Roberto, primary, Lenzi, Riccardo, additional, Marinò, Michele, additional, Latrofa, Francesco, additional, Nardi, Marco, additional, Piaggi, Paolo, additional, Mazzi, Barbara, additional, Altea, Maria Antonietta, additional, Pinchera, Aldo, additional, Vitti, Paolo, additional, Marcocci, Claudio, additional, and Sellari-Franceschini, Stefano, additional

Published
2012
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20. LOW PREVALENCE OF THE SOMATIC M918T RET MUTATION IN MICRO-MEDULLARY THYROID CANCER

Author

romei, cristina, primary, Ugolini, Clara, additional, Cosci, Barbara, additional, torregrossa, liborio, additional, Vivaldi, Agnese, additional, Ciampi, Raffaele, additional, Tacito, Alessia, additional, Basolo, Fulvio, additional, Materazzi, Gabriele, additional, Miccoli, Paolo, additional, Vitti, Paolo, additional, Pinchera, Aldo, additional, and Elisei, Rossella, additional

Published
2012
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21. Higher Intratumoral Expression of CD1a, Tryptase, and CD68 in a Follicular Variant of Papillary Thyroid Carcinoma Compared to Adenomas: Correlation with Clinical and Pathological Parameters

Author

Proietti, Agnese, primary, Ugolini, Clara, additional, Melillo, Rosa Marina, additional, Crisman, Giuliana, additional, Elisei, Rossella, additional, Santoro, Massimo, additional, Minuto, Michele, additional, Vitti, Paolo, additional, Miccoli, Paolo, additional, and Basolo, Fulvio, additional

Published
2011
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22. Radioiodine 131I Treatment for Large Nodular Goiter: Recombinant Human Thyrotropin Allows the Reduction of Radioiodine 131I Activity to Be Administered in Patients with Low Uptake

Author

Ceccarelli, Claudia, primary, Antonangeli, Lucia, additional, Brozzi, Federica, additional, Bianchi, Francesca, additional, Tonacchera, Massimo, additional, Santini, Pierina, additional, Mazzeo, Salvatore, additional, Bencivelli, Walter, additional, Pinchera, Aldo, additional, and Vitti, Paolo, additional

Published
2011
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25. CXC Chemokine Receptor 4 Immunodetection in the Follicular Variant of Papillary Thyroid Carcinoma: Comparison to Galectin-3 and Hector Battifora Mesothelial Cell-1

Author

Torregrossa, Liborio, primary, Faviana, Pinuccia, additional, Filice, Maria Elena, additional, Materazzi, Gabriele, additional, Miccoli, Paolo, additional, Vitti, Paolo, additional, Fontanini, Gabriella, additional, Melillo, Rosa Marina, additional, Santoro, Massimo, additional, and Basolo, Fulvio, additional

Published
2010
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26. Congenital Hypothyroidism and Late-Onset Goiter: Identification and Characterization of a Novel Mutation in the Sodium/Iodide Symporter of the Proband and Family Members

Author

Montanelli, Lucia, primary, Agretti, Patrizia, additional, Marco, Giuseppina de, additional, Bagattini, Brunella, additional, Ceccarelli, Claudia, additional, Brozzi, Federica, additional, Lettiero, Teresa, additional, Cerbone, Manuela, additional, Vitti, Paolo, additional, Salerno, Mariacarolina, additional, Pinchera, Aldo, additional, and Tonacchera, Massimo, additional

Published
2009
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28. Thyroid Function and Exposure to Styrene

Author

Santini, Ferruccio, primary, Mantovani, Alberto, additional, Cristaudo, Alfonso, additional, Rago, Teresa, additional, Marsili, Alessandro, additional, Buselli, Rodolfo, additional, Mignani, Aldo, additional, Ceccarini, Giovanni, additional, Bastillo, Rosalinda, additional, Taddei, Donatella, additional, Ricco, Ilaria, additional, Vitti, Paolo, additional, and Pinchera, Aldo, additional

Published
2008
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31. Thyroid Color Flow Doppler Sonography: An Adjunctive Tool for Differentiating Patients with Inappropriate Thyrotropin (TSH) Secretion Due to TSH-Secreting Pituitary Adenoma or Resistance to Thyroid Hormone

Author

Bogazzi, Fausto, primary, Manetti, Luca, additional, Tomisti, Luca, additional, Rossi, Giuseppe, additional, Cosci, Chiara, additional, Sardella, Chiara, additional, Bartalena, Luigi, additional, Gasperi, Maurizio, additional, Macchia, Enrico, additional, Vitti, Paolo, additional, and Martino, Enio, additional

Published
2006
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33. Activating Thyrotropin Receptor Mutations in Histologically Heterogeneous Hyperfunctioning Nodules of Multinodular Goiter

Author

TONACCHERA, MASSIMO, primary, VITTI, PAOLO, additional, AGRETTI, PATRIZIA, additional, GIULIANETTI, BARBARA, additional, MAZZI, BARBARA, additional, CAVALIERE, ROSSANA, additional, CECCARINI, GIOVANNI, additional, FIORE, EMILIO, additional, VIACAVA, PAOLO, additional, NACCARATO, ANTONIO, additional, PINCHERA, ALDO, additional, and CHIOVATO, LUCA, additional

Published
1998
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36. Genetic Analysis of TTF-2 Gene in Children with Congenital Hypothyroidism and Cleft Palate, Congenital Hypothyroidism, or Isolated Cleft Palate

Author

Tonacchera, Massimo, Banco, Mariaelena, Lapi, Paola, Di Cosmo, Caterina, Perri, Anna, Montanelli, Lucia, Moschini, Lidia, Gatti, Gianluca, Gandini, Daniele, Massei, Alessandro, Agretti, Patrizia, De Marco, Giuseppina, Vitti, Paolo, Chiovato, Luca, and Pinchera, Aldo

Abstract

Homozygous null mice for thyroid transcription factor (TTF)-2 gene exhibit cleft palate and thyroid malformation. We performed a genetic analysis of the TTF-2 gene in 2 children with congenital hypothyroidism (CH) and cleft palate, 45 children with thyroid dysgenesis, 19 children with isolated cleft palate or cleft lip, 4 patients with thyroid hemiagenesis. The entire coding-region of the TTF-2 gene was analyzed by direct sequencing. Direct sequencing of the TTF-2 gene revealed polymorphisms in the length of the polyalanine tract. The most frequent stretch length was 14 residues and it was found in 50 of 70 (71%) and in 45 of 53 (85%) normal healthy controls. A polyalanine tract of 16 residues in the heterozygous state was seen in 18 of 70 (26%) cases and in 4 of 53 (7%) normal subjects. In 1 of 4 (25%) case of hemiagenesis a polyalanine tract of 16 residues in the homozygous state was observed. In 1 of 26 agenesis the polyalanine tract consisted of 12 residues in the heterozygous state. Direct sequencing also revealed the presence of two silent polymorphisms. No mutations were identified in the TTF-2 gene. In conclusion, our results show that no genetic alteration was present in the TTF-2 gene of these patients, suggesting that defects in the TTF-2 gene are a rare event.

Published
2004
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