1. Enrichment and Identification of Neural Stem Cells in Neurospheres Using Rigidity-Tunable Gels
- Author
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Yukai Zeng, Keng-Hwee Chiam, Mike Yuan Hong Yu, Sweelin Chew, Sohail Ahmed, and David Aik-Aun Khoo
- Subjects
Myosin Light Chains ,0206 medical engineering ,Biomedical Engineering ,Lewis X Antigen ,Bioengineering ,02 engineering and technology ,Models, Biological ,Biochemistry ,Biomaterials ,Extracellular matrix ,03 medical and health sciences ,Rigidity (electromagnetism) ,Neural Stem Cells ,Stem cell fate specification ,Spheroids, Cellular ,Neurosphere ,Humans ,Phosphorylation ,Cell Shape ,Cell Size ,030304 developmental biology ,0303 health sciences ,Chemistry ,Asymmetric Cell Division ,Spheroid ,020601 biomedical engineering ,Neural stem cell ,Cell biology ,embryonic structures ,Identification (biology) ,Stress, Mechanical ,Stem cell ,Gels - Abstract
Stem cell fate specification is known to be regulated by mechanical cues such as cell–cell interaction and the rigidity of the extracellular matrix (ECM). At present, spheroid cultures of stem cell...
- Published
- 2019
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