1. The interaction of disulfiram and H
- Author
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Ethan, Read, Jarod, Milford, Jiechun, Zhu, Lingyun, Wu, Marc, Bilodeau, and Guangdong, Yang
- Subjects
Cell Survival ,Liver Neoplasms ,Acetaldehyde Dehydrogenase Inhibitors ,Temperature ,Antineoplastic Agents ,Aldehyde Dehydrogenase ,Hydrogen-Ion Concentration ,Mice ,Liver ,Cell Line, Tumor ,Disulfiram ,Animals ,Humans ,Hydrogen Sulfide ,Copper ,Alcohol Deterrents ,Cell Proliferation - Abstract
Disulfiram (DSF), a sulfur-containing compound, has been used to treat chronic alcoholism and cancer for decades by inactivating aldehyde dehydrogenase (ALDH). Hydrogen sulfide (H
- Published
- 2021