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Start Over Author "Pokorny K" Journal transfusion science
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2. Double-lumen inferior vena cava catheters for peripheral stem cell apheresis and transplantations.

Author

Haire WD, Stephens LC, Kotulak GD, Schmit-Pokorny K, and Kessinger A

Subjects
Adult, Aged, Aspirin therapeutic use, Bacteremia etiology, Catheterization, Central Venous adverse effects, Equipment Design, Female, Humans, Life Tables, Male, Middle Aged, Neoplasms blood, Neoplasms therapy, Thrombosis etiology, Thrombosis prevention & control, Treatment Outcome, Catheterization, Central Venous instrumentation, Hematopoietic Stem Cell Transplantation instrumentation, Hematopoietic Stem Cells, Leukapheresis instrumentation, Vena Cava, Inferior
Abstract

No previously published studies have described double-lumen hemodialysis/apheresis catheters for use with continuous-flow apheresis collection of peripheral stem cell (PSC). We prospectively evaluated experiences with these catheters during both PSC collection and transplantation. Because of previously-described successful experiences with single-lumen apheresis catheters placed in the inferior vena cava, all catheters evaluated in this study were placed in this anatomic location. Our experience demonstrated high rates of thrombotic occlusion (65%) and catheter-related infections (15%). This method of access should not be considered optimal in its present state of use. Further investigation into preferred catheter design, anatomic location, and thrombosis prophylaxis during continuous-flow apheresis is warranted.

Published
1995
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