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Your search keyword '"Hachem, Ramsey R."' showing total 9 results
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9 results on '"Hachem, Ramsey R."'

5. Hyperammonemia Syndrome After Lung Transplantation

Author

Chen, Catherine, primary, Bain, Karen B., additional, Iuppa, Jennifer A., additional, Yusen, Roger D., additional, Byers, Derek E., additional, Patterson, George A., additional, Trulock, Elbert P., additional, Hachem, Ramsey R., additional, and Witt, Chad A., additional

Published
2016
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9. Chronic Lung Allograft Dysfunction: Clinical Manifestations and Immunologic Mechanisms.

Author

Bery AI, Belousova N, Hachem RR, Roux A, and Kreisel D

Abstract

The term "chronic lung allograft dysfunction" has emerged to describe the clinical syndrome of progressive, largely irreversible dysfunction of pulmonary allografts. This umbrella term comprises 2 major clinical phenotypes: bronchiolitis obliterans syndrome and restrictive allograft syndrome. Here, we discuss the clinical manifestations, diagnostic challenges, and potential therapeutic avenues to address this major barrier to improved long-term outcomes. In addition, we review the immunologic mechanisms thought to propagate each phenotype of chronic lung allograft dysfunction, discuss the various models used to study this process, describe potential therapeutic targets, and identify key unknowns that must be evaluated by future research strategies., Competing Interests: The authors declare no conflicts of interest., (Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.)

Published
2024
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