Search

Your search keyword '"Faraci, Maura"' showing total 11 results
Start Over Author "Faraci, Maura" Journal transplantation and cellular therapy
11 results on '"Faraci, Maura"'

1. Phase II Study of Allogeneic Hematopoietic Stem Cell Transplantation for Children with High-Risk Neuroblastoma Using a Reduced-Intensity Conditioning Regimen: Results from the AIEOP Trial

Author

Prete, Arcangelo, primary, Lanino, Edoardo, additional, Saglio, Francesco, additional, Biffi, Alessandra, additional, Calore, Elisabetta, additional, Faraci, Maura, additional, Rondelli, Roberto, additional, Favre, Claudio, additional, Zecca, Marco, additional, Casazza, Gabriella, additional, Porta, Fulvio, additional, Luksch, Roberto, additional, Cesaro, Simone, additional, Rabusin, Marco, additional, Parasole, Rosanna, additional, Mura, Rosa Maria, additional, Lo Nigro, Luca, additional, Leardini, Davide, additional, Pagliara, Daria, additional, Locatelli, Franco, additional, and Fagioli, Franca, additional

Published
2024
Full Text
View/download PDF

2. Umbilical Cord Blood Transplantation for Fanconi Anemia With a Special Focus on Late Complications: a Study on Behalf of Eurocord and SAAWP-EBMT

Author

Rafii, Hanadi, primary, Volt, Fernanda, additional, Bierings, Marc, additional, Dalle, Jean-Hugues, additional, Ayas, Mouhab, additional, Rihani, Rawad, additional, Faraci, Maura, additional, de Simone, Giuseppina, additional, Sengeloev, Henrik, additional, Passweg, Jakob, additional, Cavazzana, Marina, additional, Costello, Regis, additional, Maertens, Johan, additional, Biffi, Alessandra, additional, Johansson, Jan-Erik, additional, Montoro, Juan, additional, Guepin, Gabrielle Roth, additional, Diaz, Miguel Angel, additional, Sirvent, Anne, additional, Kenzey, Chantal, additional, Rivera Franco, Monica M., additional, Cappelli, Barbara, additional, Scigliuolo, Graziana Maria, additional, Rocha, Vanderson, additional, Ruggeri, Annalisa, additional, Risitano, Antonio, additional, De Latour, Regis Peffault, additional, and Gluckman, Eliane, additional

Published
2024
Full Text
View/download PDF

3. Long-Term Complications after Allogeneic Hematopoietic Stem Cell Transplantation with Treosulfan- or Busulfan-Based Conditioning in Pediatric Patients with Acute Leukemia or Myelodysplastic Syndrome: Results of an Associazione Italiana Ematologia Oncologia Pediatrica Retrospective Study

Author

Saglio, Francesco, Pagliara, Daria, Zecca, Marco, Balduzzi, Adriana, Cattoni, Alessandro, Prete, Arcangelo, Tambaro, Francesco Paolo, Faraci, Maura, Calore, Elisabetta, Locatelli, Franco, and Fagioli, Franca

Published
2024
Full Text
View/download PDF

5. Outcomes of Unmanipulated Haploidentical Transplantation Using Post-Transplant Cyclophosphamide (PT-Cy) in Pediatric Patients With Acute Lymphoblastic Leukemia

Author

Ruggeri, Annalisa, Galimard, Jacques-Emmanuel, Paina, Olesya, Fagioli, Franca, Tbakhi, Abdelghani, Yesilipek, Akif, Navarro, José Maria Fernandez, Faraci, Maura, Hamladji, Rose-Marie, Skorobogatova, Elena, Al-Seraihy, Amal, Sundin, Mikael, Herrera, Concepcion, Rifón, Jose, Dalissier, Arnaud, Locatelli, Franco, Rocha, Vanderson, and Corbacioglu, Selim

Published
2021
Full Text
View/download PDF

6. Impact of in vivo lymphodepletion on outcome in children with non-malignant disorders receiving peripheral blood stem cell transplantation

Author

Ottaviano, Giorgio, primary, Achini-Gutzwiller, Federica, additional, Kalwak, Krzysztof, additional, Lanino, Edoardo, additional, Faraci, Maura, additional, Rao, Kanchan, additional, Chiesa, Robert, additional, Amrolia, Persis, additional, Bonanomi, Sonia, additional, Rovelli, Attilio, additional, Veys, Paul, additional, Lankester, Arjan, additional, Balduzzi, Adriana, additional, and Lucchini, Giovanna, additional

Published
2021
Full Text
View/download PDF

7. Treatment (Tx) Duration, Symptom Resolution, and Survival in Defibrotide (DF)-Treated Patients (pts) with Severe Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) after Hematopoietic Cell Transplantation (HCT): Analysis of a Multinational, Prospective, Observational Registry Study

Author

Locatelli, Franco, primary, Faraci, Maura, additional, Yakoub-Agha, Ibrahim, additional, Wheeler, Kate, additional, Ryan, Robert J., additional, Hanvesakul, Raj, additional, and Mohty, Mohamed, additional

Published
2021
Full Text
View/download PDF

8. Stem Cell Transplantation for Diamond–Blackfan Anemia. A Retrospective Study on Behalf of the Severe Aplastic Anemia Working Party of the European Blood and Marrow Transplantation Group (EBMT)

Author

Miano, Maurizio, primary, Eikema, Dirk-Jan, additional, de la Fuente, Josu, additional, Bosman, Paul, additional, Ghavamzadeh, Ardeshir, additional, Smiers, Frans, additional, Sengeløv, Henrik, additional, Yesilipek, Akif, additional, Formankova, Renata, additional, Bader, Peter, additional, Díaz Pérez, Miguel Ángel, additional, Bertrand, Yves, additional, Niemeyer, Charlotte, additional, Diallo, Safiatou, additional, Ansari, Marc, additional, Bykova, Tatiana A, additional, Faraci, Maura, additional, Bonanomi, Sonia, additional, Gozdzik, Jolanta, additional, Satti, Tariq Mahmood, additional, Bodova, Ivana, additional, Wölfl, Matthias, additional, Rocha, Vanderson G., additional, Mellgren, Karin, additional, Rascon, Jelena, additional, Holter, Wolfgang, additional, Lange, Andrzej, additional, Meisel, Roland, additional, Beguin, Yves, additional, Mozo, Yasmina, additional, Kriván, Gergely, additional, Sirvent, Anne, additional, Bruno, Benedicte, additional, Dalle, Jean Hugues, additional, Onofrillo, Daniela, additional, Giardino, Stefano, additional, Risitano, Antonio M., additional, de Latour, Régis Peffault, additional, and Dufour, Carlo, additional

Published
2021
Full Text
View/download PDF

9. Impact of in Vivo Lymphodepletion on Outcome in Children with Nonmalignant Disorders Receiving Peripheral Blood Stem Cell Transplantation

Author

Ottaviano, Giorgio, Achini-Gutzwiller, Federica, Kalwak, Krzysztof, Lanino, Edoardo, Faraci, Maura, Rao, Kanchan, Chiesa, Robert, Amrolia, Persis, Bonanomi, Sonia, Rovelli, Attilio, Veys, Paul, Lankester, Arjan, Balduzzi, Adriana, and Lucchini, Giovanna

Abstract

•Different serotherapy strategies did not provide a survival advantage in children affected by nonmalignant disorders receiving peripheral blood stem cell transplantation (PBSCT).•A higher rate of severe acute graft-versus-host disease occurred in patients receiving antithymocyte globulin.•Alemtuzumab negatively impacted T cell recovery in the first 3 months after PBSCT.

Published
2021
Full Text
View/download PDF

11. Haploidentical Stem Cell Transplantation After TCR-αβ+and CD19+Cells Depletion In Children With Congenital Non-Malignant Disease

Author

Giardino, Stefano, Bagnasco, Francesca, Falco, Michela, Miano, Maurizio, Pierri, Filomena, Risso, Marco, Terranova, Paola, Di Martino, Daniela, Massaccesi, Erika, Ricci, Margherita, Chianucci, Benedetta, Dell'Orso, Gianluca, Sabatini, Federica, Podestà, Marina, Lanino, Edoardo, and Faraci, Maura

Abstract

Haploidentical hematopoietic stem cell transplantation (haplo-HSCT) represents a valuable alternative for children with nonmalignant disease and ex vivo negative selection of TCR-αβ+cells is an emerging graft manipulation option that carries several potential advantages in terms of reduced risk of graft-versus-host disease (GvHD) and improved immune reconstitution. We report all consecutive patients with a diagnosis of nonmalignant disease who received a TCR-αβ+and CD19+depleted haplo-HSCT at “IRCCS Istituto Giannina Gaslini” from 2013 to 2019; the conditioning regimen was myeloablative or non-myeloablative, depending on underlying disease; all patients received antithymocyte globulin and rituximab. No post-transplantation GvHD prophylaxis was given in presence of a TCR-αβ+cell dose in the graft lower than the threshold of 1 × 105/kg of the recipient's weight. Among 20 HSCTs, engraftment occurred in 17 (85%) after a median of 14 and 12 days from graft infusion for neutrophils and platelets, respectively. Primary graft failure was diagnosed in 3 (15%) patients, and 2 (10%) experienced secondary rejection; all of these patients underwent a second HSCT. The cumulative incidence of a-GvHD and c-GvHD was 15% (2 = grade 1, 1 = grade 4) at 90 days and 5% (1 = grade 1) at 7 months, respectively. Cytomegalovirus reactivation requiring pre-emptive treatment was observed in 9 patients (45%). One patient developed a JC virus–related progressive multifocal leukoencephalopathy, successfully managed with donor-derived virus-specific T-cell infusions. A complete immunological recovery was reached in most patients within 6 months. After a median follow-up of 4 years, 18 patients are alive, with a cumulative survival probability of 90%. Haplo-HSCT after ex vivo TCR-αβ+/CD19+negative selection may be considered a good option for children with nonmalignant diseases because it ensures a high engraftment rate with an acceptable risk of graft failure, very low incidence of significant GvHD, and good immune reconstitution with low frequency of severe virus-related disease. However, the control of viral infection/reactivation should be kept high to promptly provide pre-emptive treatments and approaches of antiviral adoptive immunotherapy.

Published
2022
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results