1. Incidence and clinical outcomes of ventilator-associated pneumonia in liver transplant and non-liver transplant surgical patients
- Author
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Stefania Cocchi, C.M. Pellegrino, F. Di Benedetto, Massimo Girardis, S. Assenza, and Mauro Codeluppi
- Subjects
medicine.medical_specialty ,medicine.medical_treatment ,Population ,Liver transplantation ,Postoperative Complications ,Internal medicine ,medicine ,Humans ,education ,Retrospective Studies ,Transplantation ,education.field_of_study ,Surgical Procedures ,business.industry ,Mortality rate ,Incidence ,Ventilator-associated pneumonia ,Pneumonia, Ventilator-Associated ,Retrospective cohort study ,Pneumonia ,bacterial infections and mycoses ,medicine.disease ,Operative ,respiratory tract diseases ,Surgery ,Liver Transplantation ,Ventilator-Associated ,Intensive Care Units ,surgical procedures, operative ,Treatment Outcome ,SAPS II ,Surgical Procedures, Operative ,business ,Complication - Abstract
The aim of this study was to compare the incidence of ventilator-associated pneumonia (VAP) and clinical outcome among patients undergoing orthotopic liver transplantation (OLT) admitted to our surgical intensive care unit (ICU). Patients with an ICU stay longer than 4 days who had undergone surgery within 48 hours of admission were included in the study. Patients were subdivided into a liver transplant group (OLT) and no-liver transplant group (noLT). Diagnosis of VAP was based on microbiological data with a positive culture from a sample collected ≥48 hours after admission. VAP was defined as early if the positive culture occurred within the 4th day of admission, and late if after the 4th day. Three hundred seventy-three noLT and 71 OLT patients showed no differences in sex, mean severity score on admission (SAPS II), length of stay, and outcomes. The incidence of VAP was also similar in the 2 groups (27.3% in the noLT group vs 25.3% in the OLT group). Both in the OLT and noLT groups, the VAP patients showed higher (P
- Published
- 2008